Results 261 to 270 of about 886,649 (291)

Silent Philadelphia Chromosome

Cancer Genetics and Cytogenetics, 2000
In this paper, a patient is described who presented with peripheral blood and bone marrow features uncharacteristic of chronic granulocytic leukemia, which proved to be Philadelphia (Ph) chromosome-positive by metaphase and interphase cytogenetic analyses but lacked the p210 type of BCR/ABL fusion gene mRNA product by two different sensitive RT-PCR ...
János A. Vass, Karoly Szuhai, László Pajor, Molnár L, Pál Jáksó, László Kereskai   +5 more
openaire   +3 more sources

The occurrence of the Philadelphia chromosome in essential thrombocytosis

Human Genetics, 1981
The Philadelphia chromosome, assessed with banding techniques, was detected in 98.3% of bone marrow cells of a 46-year-old black female presenting with essential thrombocytosis. The patient has been followed for the past two years with no signs of chronic myelocytic leukemia.
Barathur R. Rajendra, Demetra V. Rose, Michael J. Nissenblatt, Leonard J. Sciorra, Gary Gartenberg, Ming-liang Lee   +5 more
openaire   +2 more sources

Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial.

The Lancet Haematology, 2022
E. Jabbour, N. Short, N. Jain, Xuelin Huang, G. Montalban-Bravo, P. Banerjee, K. Rezvani, Xianli Jiang, Kun-Hee Kim, R. Kanagal-Shamanna, J. Khoury, K. Patel, T. Kadia, N. Daver, K. Chien, Y. Alvarado, G. Garcia-Manero, G. Issa, F. Haddad, M. Kwari, J. Thankachan, R. Delumpa, W. Macaron, Rebecca E. Garris, M. Konopleva, F. Ravandi, H. Kantarjian   +26 more
semanticscholar   +1 more source

Ponatinib in the treatment of chronic myeloid leukemia and philadelphia chromosome positive acute lymphoblastic leukemia.

Future Oncology, 2019
Philadelphia chromosome, reciprocal translocation between chromosome 9 and 22, leading to a constitutively active fusion protein BCR-ABL1 is the common feature among Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL) and chronic myeloid ...
C. Pavlovsky, O. Chan, Chetasi Talati, J. Pinilla-Ibarz   +3 more
semanticscholar   +1 more source

Myeloblastenleukämie mit Philadelphia-Chromosom

Klinische Wochenschrift, 1967
Bei einem fruher wegen Larynx-Carcinoms mit Rontgenstrahlen behandelten Mann trat 3 Jahre spater eine Myeloblasten-Leukamie auf. Bei den cytogenetischen Untersuchungen wurden neben dem Vorkommen des Philadelphia-Chromosoms weitere Chromosomenaberrationen in der Gruppe F und G sowie eine Polymorphie des Y-Chromosoms gefunden.
Helmut Martin, M. Hussein Khan
openaire   +2 more sources

The Philadelphia or Short Y Chromosome

JAMA: The Journal of the American Medical Association, 1974
To the Editor.— In the case of the patient with erythroleukemia and Philadelphia (Ph') chromosome described by Pacheco et al (226:787, 1973), the sex of the patient is not stated. Since erythrocytic glucose-6-phosphate dehydrogenase deficiency was also present, we suspect that the patient was a man.
Michael P. Corder, Eugene P. Flannery
openaire   +2 more sources

Acute Myeloid Leukaemia with the Philadelphia Chromosome

Scandinavian Journal of Haematology, 1977
A case report of serial chromosome studies on a 26‐year‐old male with acute myeloid leukaemia (AML) is presented. The classic Philadelphia chromosome (Ph1) transloca‐tion, t (9; 22) was found in 77 % of the metaphases at diagnosis and in 100 % in relapse; during a 3‐month remission period the cytogenetic picture was normal or the Ph1 was present in a ...
Felix Mitelman, Inge Olsson, Anita Gustavsson   +2 more
openaire   +3 more sources

The Philadelphia Chromosome and Some Others

Annals of Internal Medicine, 1964
Excerpt The appearance elsewhere in this issue of three papers on chromosome studies in chronic granulocytic leukemia (CGL) has suggested that some sort of stock-taking is in order concerning the p...
openaire   +3 more sources

Targeting BCR-Abl in the treatment of Philadelphia-chromosome positive chronic myelogenous leukemia.

Pharmacological Research, 2022
R. Roskoski
semanticscholar   +1 more source

Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.

New England Journal of Medicine, 2022
R. Foà, S. Chiaretti
semanticscholar   +1 more source