Results 71 to 80 of about 20,071 (276)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Revisión biogeográfica de los marsupiales del Parque Nacional del Manú, Perú

open access: yesEspacio y Desarrollo, 1991
Se revisó los datos biogeográficos de las 9 especies de marsupiales presentes en el Parque Nacional del Manú, Estación Biológica de Cocha Cashu y Puesto de Pakitza, según fuentes escritas, datos de colecta de los museos de Historia Natural de la ...
Bethzabé Guevara Gálvez
doaj  

Cooperation and Stability through Periodic Impulse [PDF]

open access: yes, 2010
Basic games, where each individual chooses between two strategies, illustrate several issues that immediately emerge from the standard approach that applies strategic reasoning, based on rational decisions, to predict population behavior where no ...
Cressman, Ross, Tao, Yi, Zhang, Bo-Yu
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Experimental and numerical investigation into the behavior of shape memory alloys

open access: yesJournal of the Mechanical Behavior of Materials, 2012
Research and development of smart alignment systems is currently being undertaken at the Smart Devices and MEMS Laboratory at the Cape Peninsula University of Technology.
Philander Oscar   +2 more
doaj   +1 more source

Morphometric analysis of the patella and patellar ligament of South Africans of European ancestry

open access: yesSouth African Journal of Science, 2013
Morphometric analyses of the patella and patellar ligament have been reported to be important in human identification, in knee implant design and in certain surgical procedures of the knee.
Oladiran I. Olateju   +2 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Playing by the rules: Government regulation and consumer trust in the online poker industry

open access: yesComputers in Human Behavior Reports
This study examines how government regulation can affect consumer trust and the perceived value of digital services. Data from interviews, a focus group, and a discrete choice experiment conducted by online poker players find that regulation ...
Kahlil S. Philander, Bradley S. Wimmer
doaj   +1 more source

Humoral Immune Response Kinetics in Philander opossum and Didelphis marsupialis Infected and Immunized by Trypanosoma cruzi Employing an Immunofluorescence Antibody Test

open access: yesMemorias do Instituto Oswaldo Cruz, 1999
Philander opossum and Didelphis marsupialis considered the most ancient mammals and an evolutionary success, maintain parasitism by Trypanosoma cruzi without developing any apparent disease or important tissue lesion.
Ana Paula Legey   +4 more
doaj   +1 more source

Description of a new actinosporean type from South African freshwater [PDF]

open access: yes, 2004
The 1st report on actinospores described these organisms as parasites related to myxosporeans. For a long time this group of parasites was believed to represent an independent taxonomic entity.
Avenant-Oldewage, Annemarie   +2 more
core   +1 more source

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