Results 21 to 30 of about 603,267 (300)

Ventas jurisdiccionales abulenses en tiempos de Felipe III y Felipe IV

open access: yesStudia Historica: Historia Moderna, 2009
RESUMEN: Este trabajo tiene por objeto dar a conocer las enajenaciones jurisdiccionales, —excluidas las ventas de oficios— llevadas a cabo por Felipe III y Felipe IV en la provincia de Ávila.
Francisco Javier LORENZO PINAR   +1 more
doaj   +2 more sources

Los libros y lecturas de un poeta áureo: Diego de Silva y Mendoza, conde de Salinas

open access: yesILCEA, 2016
Diego de Silva y Mendoza, Count of Salinas and Ribadeo, served three monarchs—Philip II, Philip III and Philip IV—in various political capacities over a period of some forty years. At the same time, he was one of the leading poets at court.
Trevor J. Dadson
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Transatlantic Mediation of Historical Knowledge across the Iberian Empire (c1580-c1640)

open access: yesE-Spania, 2014
During the time of the Political Turn in the historiography of the Iberian Empire (1580-1640), the parallel careers of the royal historiographer Antonio de Herrera and the would-be historian Francisco Caro de Torres are indicative of the developing ...
Fabien Montcher
doaj   +1 more source

Une lecture politique des Col·loquis de la insigne ciutat de Tortosa (1557) de Cristòfol Despuig

open access: yesE-Spania, 2021
This paper offers a political reading of the Col·loquis de la insigne ciutat de Tortosa (1557), by the Catalan author Cristòfol Despuig. It is dedicated to a study of some of the political and historical themes, especially the Civil War between John II ...
Mathias Ledroit
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Une reine entre ombres et lumières ou le pouvoir au féminin : le cas d’Isabelle Bourbon, reine d’Espagne, première femme de Philippe IV (1603-1644)

open access: yesGenre & Histoire, 2009
The role of French queens and their relation to power were strictly regulated, but their political influence is difficult to assess given the shadows within which they worked. In 1615, Isabelle of Bourbon, born Princess of France, married Philip of Spain
Frédérique Sicard
doaj   +1 more source

Duty, patronage and loyalty of count of Gondomar in London [PDF]

open access: yes, 2014
El sentido del deber, la obediencia, la obligación política, el patronazgo y la lealtad, además del servicio, sirvieron para entretejer una serie de dinámicas y comportamientos que explican el funcionamiento de las monarquías europeas y que permiten ...
Sanz Camañes, Porfirio
core   +1 more source

From contract to treaty: the legal transformation of the Spanish succession (1659-1713) [PDF]

open access: yes, 2011
The problem of the Spanish Succession kept the European diplomatic system in suspense from 1659 until 1713. Statesmen and diplomats tackled the question. Their practical vision of the law is a necessary complement to legal doctrine. Louis XIV and Emperor
Dhondt, Frederik
core   +2 more sources

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

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