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open access: yesPhilosophy Kitchen, 2016
Philosophy Philosophy Kitchen
doaj   +3 more sources

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

open access: yesAdvanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan   +9 more
wiley   +1 more source

Deformable Eutectic Alloy With Near‐Theoretical Yield Strength via Hierarchical Nanoscale Multiphases and Sessile Defects

open access: yesAdvanced Science, EarlyView.
A CoCrFeNiTa0.4 eutectic high‐entropy alloy achieves a near‐theoretical yield strength of 2.6 GPa with 13.6% plasticity. This breakthrough stems from a hierarchical nanostructure (FCC‐Laves lamellae with L12/D022 precipitates), which alleviates the inter‐phase modulus/hardness mismatch through synergistic strengthening and toughening, guiding the ...
Yusha Luo   +10 more
wiley   +1 more source

Philosophy and the representation of literary works in high school essays

open access: yesJournal of Philosophy in Schools
It is uncontroversial that philosophy amplifies the salience and scope of literary themes. However, it is less clear whether philosophy relates to the way in which literary texts ought to be represented in curriculum-based high school assessment tasks ...
Ben Schermbrucker
doaj   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

open access: yesAdvanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang   +9 more
wiley   +1 more source

Gutmann Donor Theory‐Guided Design of Mononuclear Ionic Cluster for Exceptional N‐Type Thermoelectric Ionogel

open access: yesAdvanced Science, EarlyView.
Super‐stretchable and self‐healing polyacrylate ternary ionogel elastomers are used for flexible i‐TE devices. Based on Gutmann donor theory of doped anion, the work proposes a three‐parameter tuning strategy of flexible polymer‐doped anion‐synergistic cation to achieve the systematic design of ionic thermoelectric materials. Abstract Quasi‐solid‐state,
Bin Chen   +9 more
wiley   +1 more source

Scarica l’intero fascicolo

open access: yesPhilosophy Kitchen, 2013
Philosophy Kitchen
doaj   +3 more sources

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