Results 41 to 50 of about 3,410 (168)

Identification of a Benzenesulfonylpiperazine Derivative With In Vivo Efficacy Against Visceral Leishmaniasis

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre, Mariza Gabriela Faleiro de Moura Lodi Cruz, Guilherme Freitas de Lima Hercos, Rafael Consolin Chelucci, Simone Michelan‐Duarte, Gisele Barbosa, Analu R. Costa, Miguel Angel Chávez‐Fumagalli, Paula Derksen Macruz, Eduardo Jorge Pilau, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Silvane Maria Fonseca Murta, Celso de Oliveira Rezende Júnior   +13 more
wiley   +1 more source

Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]

, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
core  

Phylogenetic relations among Mexican phlebotomine sand flies (Diptera: Psychodidae) and their divergence time estimation.

PLoS ONE, 2023
Phlebotomine sand flies (Diptera: Psychodidae: Phlebotominae) have biological relevance as vectors of several pathogens. To ensure periodic entomological monitoring it is necessary to have efficient and accurate tools for an adequate taxonomic ...
Yokomi N Lozano-Sardaneta, Jesús A Díaz-Cruz, Vicente Viveros-Santos, Sergio Ibáñez-Bernal, Herón Huerta, Carlos F Marina, Pedro C Mis-Ávila, Maribel Martínez-Burgos, Jorge A Torres-Monzón, Víctor Sánchez-Cordero, Ingeborg Becker   +10 more
doaj   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

Zoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda, Laryssa Fabiano do Rosário Coelho, Samanta Cristina das Chagas Xavier, Artur Augusto Velho Mendes Junior, Renan Nunes Albuquerque, Aline Fagundes da Silva, Andreza Pain Marcelino, Fernanda Nunes Santos, Sandro Antonio Pereira, Rodrigo Caldas Menezes, Armando de Oliveira Schubach   +10 more
wiley   +1 more source

Vector‐borne diseases‐knowledge maps

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Increasing the diversity of Sycorax Haliday, 1839 (Diptera: Psychodidae) in the Neotropical region: New species from the Brazilian Atlantic Forest

Austral Entomology, Volume 65, Issue 1, February 2026.
Abstract Four new species of Sycorax Haliday, 1839 are described: Sycorax alumna sp. nov., Sycorax catarina sp. nov., Sycorax paranaensis sp. nov., and Sycorax striga sp. nov., with the females of Sycorax striga sp. nov. bearing characteristics that suggest haematophagous behaviour.
Lucas Rossito, Luiz Carlos Pinho, Andrey José de Andrade   +2 more
wiley   +1 more source

Leishmaniasis Transmission Risk at the Forest‐Peridomestic Interface in an Area of Southern Sinaloa, Mexico: Entomological, Molecular, and Climatic Evidence

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
Leishmaniasis, caused by Leishmania spp. and transmitted by phlebotomine sand flies, affects almost 1,000,000 people annually across more than 90 countries. In Mexico, growing evidence of locally acquired transmission in northwestern states makes ecoepidemiological work increasingly urgent.
Juan José Ríos Tostado, Hipólito Castillo Ureta, José Israel Torres Avendaño, José Marcial Zazueta Moreno, César Enrique Romero Higareda, Luz Isela Peinado Guevara, Annete Itzel Apodaca Medina, Edith Hilario Torres Montoya, Satabdi Datta Choudhury   +8 more
wiley   +1 more source

Description of Lutzomyia chotensis, a new species of Peruvian Phlebotominae (Diptera, Psychodidae)

, 2003
Lutzomyia chotensis sp. nov. (Diptera, Psychodidae, Phlebotominae) from Cajamarca Department, Peru, is described and its taxonomic position ...
C\ue1ceres, Abraham G., Zorrilla, Victor, Galati, Eunice A. Bianchi, Galati, Eunice Aparecida Bianchi, Cáceres, Abraham G.   +4 more
core   +1 more source

Going Mobile: Using Portable Genomic Technologies for PCR‐Free In Situ Species Identification and Real‐Time Molecular Systematics

Ecology and Evolution, Volume 15, Issue 11, November 2025.
Here, we document how the implementation of a portable laboratory, in combination with targeted long‐read sequencing through an approach known as nanopore adaptive sampling, can facilitate in situ genomic and systematic analyses across a wide range of animal taxa, including multiple small mammals and blood‐feeding arthropods.
Evan J. Kipp, Marissa S. Milstein, Lexi E. Frank, Roxanne J. Larsen, Tiffany M. Wolf, Christopher Faulk, Christopher A. Shaffer, Peter A. Larsen   +7 more
wiley   +1 more source