Apoptosis of Hepatocytes Caused by Punta Toro Virus (Bunyaviridae: Phlebovirus) and Its Implication for Phlebovirus Pathogenesis [PDF]
The American Journal of Pathology, 2005 Experimental infection of hamsters with Punta Toro virus (PTV) produces a disease with clinical and pathological similarities to the severe human hemorrhagic fever caused by Rift Valley fever virus (RVFV), thus providing an animal model for RVFV pathogenesis. In this model, hepatocytic apoptosis is the main pathological component of liver injuries that
Xiaohua, Ding +4 more
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SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins [PDF]
Scientific Reports, 2018 AbstractAutophagy is essential for eukaryotic cell homeostasis and can perform both anti-viral and pro-viral roles depending on the kinds of viruses, cell types and cell environment. Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) is a newly discovered tick-borne virus in the Phenuiviridae family that causes a severe hemorrhagic fever ...
Sun, Yue +3 more
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Neuroinvasive Phlebovirus Infection in Greece: A Case Report [PDF]
Intervirology, 2014 <b><i>Objective:</i></b> Sandfly fever phleboviruses are endemic in Mediterranean countries. We report a febrile phlebovirus case in a Greek patient who presented signs of neuroinvasive infection. <b><i>Methods:</i></b> In summer 2010, a 20-year-old male was admitted to hospital with fever and lethargy ...
Anna Papa +5 more
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Fatal Tickborne Phlebovirus Infection in Captive Cheetahs, Japan [PDF]
Emerging Infectious Diseases, 2018 Two captive cheetahs from a zoo in Japan died of a severe fever with thrombocytopenia syndrome-like illness. Severe fever with thrombocytopenia syndrome virus, an endemic tickborne phlebovirus, was detected systemically with secretion of infectious viruses into the saliva.
Matsuno, Keita +14 more
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Identification of Host Factors for Rift Valley Fever Phlebovirus
Viruses, 2023 Rift Valley fever phlebovirus (RVFV) is a zoonotic pathogen that causes Rift Valley fever (RVF) in livestock and humans. Currently, there is no licensed human vaccine or antiviral drug to control RVF. Although multiple species of animals and humans are vulnerable to RVFV infection, host factors affecting susceptibility are not well understood.
Velmurugan Balaraman +12 more
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NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery [PDF]
, 2014 Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and ...
Barry, Gerald +10 more
core +3 more sources
European Network for Neglected Vectors and Vector-Borne Infections COST Action Guidelines: What Is This About and What Is This For? [PDF]
, 2017 European network for neglected vectors and vector-borne infections COST action guidelines: What Is this about and what iIs this ...
Charrel, Remi N. +3 more
core +3 more sources
Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins [PDF]
, 2017 published_or_final_versio
Benjamin Brennan +6 more
core +3 more sources
The Unique Phylogenetic Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin of the Genus Phlebovirus [PDF]
mSphere, 2018 The emergence of novel tick-borne RNA viruses causing severe illness in humans has complicated the epidemiological landscape of tick-borne diseases, requiring further investigation to safeguard public health. In the present study, we discovered a novel tick-borne phlebovirus from Ixodes persulcatus ticks in Japan ...
Keita Matsuno +15 more
openaire +4 more sources
Phlebovirus detection on phlebotomine sandflies in Lampedusa Island (Italy).
Veterinaria italiana, 2023 Phleboviruses are common human pathogens diffused on the Mediterranean area whose infection can cause the typical prodromal symptom of a mild three‑days fever. In particular, Toscana Virus (TOSV) has a great concern since its capacity to provoke central nervous system disorders like meningoencephalitis.
Stefano, Reale +6 more
openaire +2 more sources