Results 21 to 30 of about 26,986 (167)
In vitro and in vivo Phlebovirus inhibition by ribavirin [PDF]
Ribavirin (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) was markedly inhibitory in vitro to Adames and Balliet strains of Punta Toro virus (PTV), a Phlebovirus related to Rift Valley fever and sandfly fever viruses. By using inhibition of viral cytopathic effect in LLC-MK2 cells with both virus strains, the 50% effective dose was 4 to 10 ...
R W, Sidwell +3 more
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Humoral immunity to phlebovirus infection
AbstractPhleboviruses are zoonotic pathogens found in parts of Africa, Asia, Europe, and North America and cause disease symptoms ranging from self‐limiting febrile illness to severe disease, including hemorrhagic diathesis, encephalitis, and ocular pathologies.
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Circulation of Toscana Virus in a Sample Population of Corsica, France
Sandfly-borne phleboviruses pathogenic to humans, such as Toscana virus (TOSV) and sandfly fever Sicilian virus (SFSV), are endemic in the Mediterranean region.
Shirley Masse +4 more
doaj +1 more source
Apoptosis of Hepatocytes Caused by Punta Toro Virus (Bunyaviridae: Phlebovirus) and Its Implication for Phlebovirus Pathogenesis [PDF]
Experimental infection of hamsters with Punta Toro virus (PTV) produces a disease with clinical and pathological similarities to the severe human hemorrhagic fever caused by Rift Valley fever virus (RVFV), thus providing an animal model for RVFV pathogenesis. In this model, hepatocytic apoptosis is the main pathological component of liver injuries that
Xiaohua, Ding +4 more
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St. Abb’s Head phlebovirus – a separate virus species or a strain of Uukuniemi phlebovirus?
St. Abb’s Head virus (SAHV), a member of the genus Phlebovirus (family Phenuiviridae, order Bunyavirales), belongs to the largest group of negative strand RNA viruses. All phleboviruses share a genome structure that comprises three segments of negative-sense or ambi-sense RNA.
Agnieszka M Szemiel, Brian J Willett
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Background High throughput sequencing (HTS) boosted the discovery of novel viruses and new variants of known viruses. Here we investigated the presence of viruses in 12 pools of sand flies captured in three climatic periods in RAPELD grids at Rio Claro ...
Michellen S. de Carvalho +7 more
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First Isolation of Punique Virus from Sand Flies Collected in Northern Algeria
In the last decade, several phleboviruses transmitted by sand flies were detected in the Mediterranean countries, with the health impact of some of them being unknown.
Hemza Manseur +10 more
doaj +1 more source
In South Korea, nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) began during 2013. Among 301 surveillance cases, 35 hospitalized case-patients in 25 areas were confirmed by using virologic testing, and 16 (46%) case ...
Jaeseung Shin +3 more
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Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran
Phleboviruses are classified into two main groups: the sandfly fever group (transmitted by sandflies and mosquitoes) and the Uukuniemi group (transmitted by ticks).
Nariman Shahhosseini +4 more
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Emerging Sand Fly–Borne Phlebovirus in China [PDF]
عزلنا 17 سلالة فيروسية قادرة على إحداث تأثيرات اعتلال خلوي في خلايا الثدييات والموت في الفئران حديثي الولادة من ذباب الرمل في الصين. أظهر التحليل التطوري أن هذه السلالات تنتمي إلى جنس الفيروس الوريدي. تسلط هذه النتائج الضوء على الحاجة إلى السيطرة على هذا الفيروس الناشئ المحتمل للمساعدة في حماية الصحة العامة.
Jing Wang +18 more
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