Results 81 to 90 of about 39,175 (264)
Smart Molecules, EarlyView.The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang +8 more
wiley +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
Cardiometabolic Treatment Gap in Routine Psychiatric Care: A Cross‐Sectional Study of 1553 Patients
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Background People with severe mental illness (SMI) have elevated cardiometabolic morbidity and mortality, with similar concerns increasingly reported in other psychiatric conditions including anxiety disorders and ADHD. Somatic conditions are often underdiagnosed and pharmacologically undermanaged in this population.
Vincent Achour +4 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens +7 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw +5 more
wiley +1 more source
FRAME – A FRAMEwork for Objectively Measuring Fear Based on Physiological and Psychological Data
Current Directions in Biomedical EngineeringPsychological trials, such as behavioural avoidance tests (BAT), are a fundamental part of the phobia therapeutic process. In order to link physiological reactions with specific points in time during psychological trials, it is necessary to integrate ...
Grensing Florian +4 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto +44 more
wiley +1 more source
An examination of core beliefs in generalized anxiety disorder
British Journal of Clinical Psychology, EarlyView.Abstract Objective Generalised anxiety disorder (GAD) is characterised by uncontrollable worries. Cognitive behaviour therapy (CBT) is an effective treatment for GAD; however, manualised treatments rarely include interventions to target core beliefs. This study aimed to (1) explore the core beliefs about the self that are endorsed by individuals with ...
Amy E. Doust +4 more
wiley +1 more source
دور وزارة الأوقاف المصرية في التصدي لظاهرة (الاسلاموفوبيا)
Mağallaẗ Kulliyyaẗ Al-Adāb Bi-Qināالحمدُ لله رَبِّ العالَمين، والصّلاةُ والسّلامُ على أشرف المُرسلين وإمام المتقين، سيدنا مُحَمِّد، وعلىَ آله وصحبه والتّابعين، ومَنْ سار على نهْجِه إلى يوم الدين. أمّا بعد؛؛؛ فَمُنذُ بعثة النّبي لمْ يدّخِر أعداء الإسلام جَهدًا في استغلال كل الوسائل في مُ
على عبدالله السيد عبدالنبى +2 more
doaj +1 more source