Results 31 to 40 of about 13,412 (298)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

The association of anxiety and stress-related disorders with C-reactive protein (CRP) within UK Biobank

Brain, Behavior, & Immunity - Health, 2022
Anxiety and stress-related disorders are both common and disabling psychiatric conditions. There are a number of hypotheses suggesting the underlying pathophysiology of these disorders, however, the exact mechanism is unknown. Inflammation has previously
Emma Kennedy, Claire L. Niedzwiedz
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra, Tin‐Suet Joan Lee, Jacob Vorstman, Patricia Parkin, Louise Gallagher, Aneta Krakowski   +5 more
wiley   +1 more source

Precursor or sequela: pathological disorders in people with Internet addiction disorder. [PDF]

PLoS ONE, 2011
BACKGROUND: This study aimed to evaluate the roles of pathological disorders in Internet addiction disorder and identify the pathological problems in IAD, as well as explore the mental status of Internet addicts prior to addiction, including the ...
Guangheng Dong, Qilin Lu, Hui Zhou, Xuan Zhao   +3 more
doaj   +1 more source

Traumatic Experiences, Psychological Distress and Suicide‐Related Behaviors in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Autistic adults have increased risks of trauma, suicide, and poor mental health compared to non‐autistic adults, with 1 in 4 autistic adults attempting suicide. We administered an anonymized, self‐report survey to 424 autistic and 345 non‐autistic adults through a convenience sampling framework.
T. A. Chikaura, E. Weir, S. Griffiths, T. Procyshyn, M. Pelton, C. Allison, H. Hodges, S. R. White, T. Ford, S. Baron‐Cohen   +9 more
wiley   +1 more source

POSSIBILITIY OF SHORT-TERM STRESS INFLUENCES IMPLEMENTATION IN BIOLOGICALLY ACTIVE COMPOUNDS SCREENING

Фармация и фармакология (Пятигорск), 2015
This work presents the analysis of phobic anxiety behavioral reactions connected with short-term stress influences. We have established that 15 minutes forced swimming reduces locomotory and exploratory activity of animals without any connection with ...
A. S. Tarasov, E. I. Morkovin, V. V. Stepanova   +2 more
doaj   +1 more source

Exploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Restricted and repetitive behaviors (RRB) are associated with sensory processing (SP) differences for autistic people, and are thought to be a coping strategy to help manage the sensory environment. Previous work shows that, for autistic people, alexithymia, intolerance of uncertainty (IU), and anxiety mediate the relationship between SP ...
Heather L. Moore, Samuel Brice, Natalya Spraggon, Barry Ingham, Mark Freeston, Jeremy R. Parr, Jacqui Rodgers   +6 more
wiley   +1 more source

Effectiveness and cost-effectiveness of web-based treatment for phobic outpatients on a waiting list for psychotherapy: protocol of a randomised controlled trial

BMC Psychiatry, 2012
Background Phobic disorders are highly prevalent and constitute a considerable burden for patients and society. As patients wait for face-to-face psychotherapy for phobic disorders in outpatient clinics, this time can be used for guided self-help ...
Kok Robin N, van Straten Annemieke, Beekman Aartjan, Bosmans Judith, de Neef Manja, Cuijpers Pim   +5 more
doaj   +1 more source