Results 111 to 120 of about 11,891,957 (239)

A Solid‐Phase Approach to Chiral C2‐Substituted Cyclen and DOTA‐Like Lanthanoid Ligands

Chemistry – A European Journal, EarlyView.
Chiral C2‐substituted cyclen derivatives have been designed and synthesized from chiral cyclic peptoids. Their conversion into the corresponding DOTA‐type ligands opens new avenues for the development of high‐relaxivity MRI contrast agents. ABSTRACT Magnetic resonance imaging (MRI) is a powerful diagnostic modality that relies on Gd+3‐based contrast ...
Rosaria Schettini, Roberta Napolitano, Alberto Fringuello Mingo, Federica Buonsanti, Giovanni Pierri, Consiglia Tedesco, Chiara Costabile, Giorgio Della Sala, Irene Izzo, Francesco De Riccardis   +9 more
wiley   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Green systems assessment in the Solano District [PDF]

, 2014
tableOfContents: Executive summary -- Correspondence to scope of work -- Introduction -- Research design and data sources -- Sustainable green systems goals, indicators, and targets -- Sustainability of the current state of green systems -- Causal ...

core  

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Empowering Change From Within: A Human‐Centred Approach to Digital Transformation in an Italian Food Sector SME

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the challenges of digital transformation in the food sector, emphasising the strategic role of human resources (HR) as enablers of technological change. Drawing on the concept of organisational rent, it explores how sustainability‐oriented HR practices support digital adoption and enhance both economic and social ...
Vincenzo Pontrelli, Laurie Mook, Laura Berardi, Arcangelo Marrone   +3 more
wiley   +1 more source

Evaluating and Understanding Weight Management Experiences Among Adolescent Girls During and After Residential Treatment for Obesity

Obesity Science & Practice
Background Residential programs have been utilized for the treatment of adolescents with severe obesity, yet few have been evaluated. Objective The objectives were to (1) evaluate the effect of a long‐term residential treatment program focused on ...
Morgan E. Braxton, Subin Jang, Ashley M. Ruiz, Jim Hershey, Justin R. Ryder, Aaron S. Kelly, Gabriel Q. Shaibi   +6 more
doaj   +1 more source

Phoenix, 2019-09-23 [PDF]

, 2019
The Phoenix is a student newspaper published at Governors State University since August 2002.
Phoenix Newspaper,
core  

Improved Conservative Scheme for Lenard‐Bernstein Collisions in Gyrokinetic Turbulence Simulations

Contributions to Plasma Physics, EarlyView.
ABSTRACT Turbulence in the edge and scrape‐off layer regions plays a critical role for the performance of future magnetic confinement fusion power plants. Gyrokinetic simulations allow studying this regime with high fidelity. A key aspect in these regions is the high concentration of impurities, which can radiate energy, leading to significant losses ...
Andrew Ivan Sulimro, Philipp Ulbl, Jordy Trilaksono, Frank Jenko   +3 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

Michèle Phoenix

, 2016
Michèle Phoenix, TCK Advocate, World Traveler, speaks on understanding in ...
Phoenix, Michèle
core