Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
From similarity to conceptual-how pictophonetic Chinese characters facilitate inductive reasoning in 5-10-year-old children. [PDF]
Wang X, Hu N, Ma R, Cai X, Huang X.
europepmc +1 more source
Activism as education in and through the youth climate justice movement
Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley +1 more source
The cognitive impacts of Chinese pinyin learning on English-speaking elementary students in a bilingual educational setting. [PDF]
Liu J, Bai H.
europepmc +1 more source
Career motivations and perceptions of teaching of 16–19‐year‐olds in England and Wales
Abstract The current study provides an understanding of career‐related motivations of 16–19‐year‐olds in schools and A‐level colleges in England and Wales. The 672 participants (62% women) were asked to complete a modified version of the Motivations for Career Choice and the Persistence Research in Science and Engineering scales and provide comments on
Sophie Thompson‐Lee +4 more
wiley +1 more source
Sensory acuity and cross-language phonetic similarity jointly predict second language vowel production accuracy. [PDF]
Li JJ +4 more
europepmc +1 more source
Understanding the paradox of primary teacher shortage in low‐income countries: Insights from Malawi
Abstract Malawi faces a persistent and chronic teacher shortage, particularly at the primary school level, with much of the challenge attributed to teacher supply constraints. While the causes of teacher shortages are known to be complex and context‐dependent, there remains a lack of in‐depth, country‐specific research to guide effective policies ...
Peter Mtika, Edward M. Sosu
wiley +1 more source
Prosodic hierarchy and the encoding of modality: a study of L2 French statements and commands by Mandarin learners. [PDF]
Chu X, Larrivée P.
europepmc +1 more source
Understanding exam access arrangements in practice: Challenges and opportunities
Abstract Secondary students with specific learning difficulties (SpLD) often face challenges with academic tasks, particularly with high‐stakes examinations. Exam access arrangements (EAA) are provided as reasonable adjustments to reduce disadvantage for students with SpLD.
Catherine Antalek +2 more
wiley +1 more source

