Results 111 to 120 of about 1,283,777 (223)

Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence

Frontiers in Microbiology, 2017
In order to decipher the nature of the slowly growing Mycobacterium tuberculosis (M.tuberculosis) lineage 7, the differentially abundant proteins in strains of M. tuberculosis lineage 7 and lineage 4 were defined.
Solomon A. Yimer, Solomon A. Yimer, Alemayehu G. Birhanu, Alemayehu G. Birhanu, Shewit Kalayou, Tahira Riaz, Ephrem D. Zegeye, Getachew T. Beyene, Carol Holm-Hansen, Gunnstein Norheim, Markos Abebe, Abraham Aseffa, Tone Tønjum, Tone Tønjum   +13 more
doaj   +1 more source

Exploring the antifungal potential of Cannabis sativa-derived stilbenoids and cannabinoids against novel targets through in silico protein interaction profiling

Frontiers in Chemistry
Cannabinoid and stilbenoid compounds derived from Cannabis sativa were screened against eight specific fungal protein targets to identify potential antifungal agents.
Kevser Kübra Kırboğa, Aman Karim, Ecir Uğur Küçüksille, Mithun Rudrapal, Johra Khan, Raghu Ram Achar, Ekaterina Silina, Natalia Manturova, Victor Stupin   +8 more
doaj   +1 more source

The molecular basis of phosphite and hypophosphite recognition by ABC-transporters [PDF]

, 2017
Inorganic phosphate is the major bioavailable form of the essential nutrient phosphorus. However, the concentration of phosphate in most natural habitats is low enough to limit microbial growth.
Adams, N.B.P., Baker, P.J., Bibby, T.S., Bisson, C., Brindley, A.A., Hitchcock, A., Hunter, C.N., Polyviou, D., Stevenson, B.   +8 more
core   +2 more sources

On calculation of the electrostatic potential of a phosphatidylinositol phosphate-containing phosphatidylcholine lipid membrane accounting for membrane dynamics.

PLoS ONE, 2014
Many signaling events require the binding of cytoplasmic proteins to cell membranes by recognition of specific charged lipids, such as phosphoinositol-phosphates.
Jonathan C Fuller, Michael Martinez, Rebecca C Wade   +2 more
doaj   +1 more source

Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways

Journal of Lipid Research, 1997
To assess the potential for feedback inhibition by isoprene intermediates in the cholesterol and nonsterol isoprene biosynthetic pathway, we expressed human cDNAs encoding mevalonate kinase (MKase), phosphomevalonate kinase (PMKase), and mevalonate ...
D D Hinson, K L Chambliss, M J Toth, R D Tanaka, K M Gibson   +4 more
doaj   +1 more source

Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO) [PDF]

, 2017
PNPO deficiency is responsible of severe neonatal encephalopathy, responsive to pyridoxal-5’-phosphate (PLP) or pyridoxine. Recent studies widened the phenotype of this condition and detected new genetic variants on PNPO gene, whose pathogenetic role and
Carducci, Carla, Contestabile, Roberto, Di Salvo, Martino L., Guerrini, Renzo, Leuzzi, Vincenzo, Mastrangelo, Mario, Mei, Davide, Montomoli, Martino, Nogués, Isabel, Paiardini, Alessandro, Tolve, Manuela, Tramonti, Angela   +11 more
core   +2 more sources

Effect of Escherichia coli endotoxin on Archachatina marginata haemolymph coagulation system [PDF]

, 2010
The effect of _E. coli_ endotoxin on the heamolymph coagulation response of _Archachatina marginata_ was studied. Heamocyte Lysate(HL), Haemocyte Lysate Supernatant(HLS) and Haemocyte Lysate Debris (HLD) were exposed to _Escherichia coli_ endotoxin ...
Adenike Oladiji, Musa Salawu, Musa Yakubu, Nasiru Muhammad, Oyelola Oloyede   +4 more
core   +1 more source

Niobium Uptake and Release by Bacterial Ferric Ion Binding Protein

Bioinorganic Chemistry and Applications, 2010
Ferric ion binding proteins (Fbps) transport FeIII across the periplasm and are vital for the virulence of many Gram negative bacteria. Iron(III) is tightly bound in a hinged binding cleft with octahedral coordination geometry involving binding to ...
Yanbo Shi, Ian Harvey, Dominic Campopiano, Peter J. Sadler   +3 more
doaj   +1 more source

Pyridoxal phosphate binding protein (PLPBP) deficiency mimicking opsoclonus‐myoclonus‐ataxia syndrome

Annals of the Child Neurology Society
AbstractIntroductionGenetic and metabolic conditions can mimic diagnoses such as hypoxic‐ischemic encephalopathy, meningoencephalitis, epilepsy, and opsoclonus‐myoclonus‐ataxia syndrome (OMAS). Without a high index of suspicion and proper testing, diagnoses can be missed, and treatment delayed.MethodsA 3‐year‐old girl with a history of neonatal ...
Mrinmayee Takle, Dhwani Sahjwani, Diana Bharucha‐Goebel, Tyler Rapp, Cecilia Bouska, Alexandra Kornbluh, Kuntal Sen   +6 more
openaire   +2 more sources

The presence of phosphate-binding protein in inner mitochondrial membrane.

Acta medica Okayama, 1977
Phosphate-binding protein(s) was found in the inner mitochondrial membrane of calf heart by Sephadex G-200 and G-25 gel filtration. The binding activity was inhibited by N-ethylmaleimide and competed by a large amount of cold phosphate. The amount of phosphate bound to the fraction was 29 nmoles per mg of protein. Affinity chromatography with phosphate-
Hatase, Osamu, Tsutsui, Ken, Oda, Takuzo
openaire   +2 more sources