Results 231 to 240 of about 877,235 (257)

The DING Family of Phosphate Binding Proteins in Inflammatory Diseases

2014
Human paraoxonase 1 (hPON-1) is a protein that has been studied in relation to its antioxidant and anti-atherosclerotic properties. Despite extensive studies, the molecular mechanisms responsible for its functional properties remain unclear. During the last decade, a new partner of hPON-1 has been identified. Hidden for a long time because of a similar
Daniel, Gonzalez, Mikael, Elias, Eric, Chabrière   +2 more
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GUANOSINE PHOSPHATE BINDING PROTEIN COUPLED RECEPTORS IN PROSTATE CANCER: A REVIEW

Journal of Urology, 2002
Androgens are the primary growth promoters of the prostate gland and yet prostate tumors progress despite androgen ablation. This progression suggests a role for additional cellular factors in the progression to androgen independent disease. We examined the role of a family of extracellular signal regulators, namely the guanosine phosphate binding (G ...
Ganesh V, Raj, Liza, Barki-Harrington, Pao F, Kue, Yehia, Daaka   +3 more
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Tyrosine environment and phosphate binding in the archaebacterial histone-like protein HTa

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1988
Abstract The thermophilic Archaebacterium, Thermoplasma acidophilum , has a DNA-stabilizing protein bound to its DNA. Each polypeptide chain of the protein contains only a single tyrosine residue. The protein exists normally as a complex of four identical subunits.
Searcy, DG, MONTENAYGARESTIER, T, LASTON, DJ, HELENE, C   +3 more
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Regulation of early-endosome dynamics by phosphatidylinositol 3-phosphate binding proteins

Biochemical Society Transactions, 1999
Introduction The endocytic pathway plays an important role in regulating the activities of signalling receptors. Experiments that block the clathrin-mediated internalization of epidermal growth factor receptors have shown that the relative strengths of various signalling pathways associated with the activated receptor are significantly altered as a ...
Clague, M J, Jones, A T, Mills, I G, Walker, D M, Urbé, S   +4 more
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Potentiometric phosphate-sensing system utilizing phosphate-binding protein

Analytical and Bioanalytical Chemistry, 2002
A phosphate-detection system has been developed which uses phosphate-binding protein (PBP) from Escherichia coli. PBP was immobilized on a sheet of nitrocellulose membrane by cross-linking and the membrane potential of the immobilized PBP was measured. The response time of the system to phosphate was 5 min. The response was selective to phosphate among
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A Biosensor for Inorganic Phosphate Using a Rhodamine-Labeled Phosphate Binding Protein

Biochemistry, 2006
A novel biosensor for inorganic phosphate (Pi) has been developed based on the phosphate binding protein of Escherichia coli. Two cysteine mutations were introduced and labeled with 6-iodoacetamidotetramethylrhodamine. When physically close to each other and correctly oriented, two rhodamine dyes interact to form a noncovalent dimer.
Michael P, Okoh, Jackie L, Hunter, John E T, Corrie, Martin R, Webb   +3 more
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Phosphate-binding proteins and peptides: from molecular mechanisms to potential applications

Current Opinion in Biotechnology
Selective binding of phosphate is vital to multiple aims including phosphate transport into cells and phosphate-targeted applications such as adsorption-based water treatment and sensing. High-affinity phosphate-binding proteins and peptides offer a nature-inspired means of efficiently binding and separating phosphate from complex matrices. The binding
Brooke K Mayer, Justin M Hutchison, Eric S McLamore, Maria Torres, Kaushik Venkiteshwaran   +4 more
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Dissection of the Nucleotide and Metal−Phosphate Binding Sites in cAMP-Dependent Protein Kinase

Biochemistry, 1999
The catalytic (C) subunit of cAMP-dependent protein kinase (cAPK) is more stable by several criteria when it is part of a holoenzyme complex. By measuring the thermal stability of the free C subunit in the presence and absence of nucleotides and/or divalent metal ions, it was found that most of the stabilizing effects associated with the type I ...
F W, Herberg, M L, Doyle, S, Cox, S S, Taylor   +3 more
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A Structural Analysis of Phosphate and Sulphate Binding Sites in Proteins Estimation of Propensities for Binding and Conservation of Phosphate Binding Sites

Journal of Molecular Biology, 1994
Geoffrey J Barton
exaly  

A Structural Analysis of Phosphate and Sulphate Binding Sites in Proteins

Journal of Molecular Biology, 1994
Geoffrey J Barton
exaly