Results 161 to 170 of about 2,125,818 (314)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Phosphate: Not Just a CKD Problem? [PDF]

Kidney360
Pao AC, Raphael KL.
europepmc   +1 more source

Calcium Phosphate Research in Australia

Calcium phosphate research in Australia has originated from studies on natural minerals – biological deposits in teeth and in nature. This review surveys the research in the different regions in Australia and shows the most activity in Victoria and New ...
Gross, Kārlis-Agris
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Hypophosphatemic rickets: diagnosis and treatment. [PDF]

Arch Endocrinol Metab
Bruneau H, Bergwitz C.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Corrigendum: The presence of silver nanoparticles reduces demand for dissolved phosphorus to the benefit of biological nitrogen fixation in the coastal eastern Mediterranean Sea

Frontiers in Marine Science, 2023
Andrew P. Rees, Eleonora Faraggiana, Eleonora Faraggiana, Karen Tait, Mauro Celussi, Eleni Dafnomilli, Vincenzo Manna, Andrew Manning, Paraskevi Pitta, Anastasia Tsiola, Snežana Živanović   +10 more
doaj   +1 more source

Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift. [PDF]

Proc Natl Acad Sci U S A
White ML, Mortier J, Granqvist L, Omnus DJ, Louski M, Crang N, Aldikacti B, Migeot V, Chien P, Hennequart M, Hallez R, Jonas K.   +11 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Treatment Satisfaction with Tenapanor: Real-World Survey of Patients with End-Stage Renal Disease and Hyperphosphatemia. [PDF]

Patient Prefer Adherence
Kendrick JB, Scott LL, Gist B, Williams LA.   +3 more
europepmc   +1 more source