Results 201 to 210 of about 138,912 (309)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA. [PDF]

Nat Commun
Whitfield HL, Gilmartin M, Riley AM, Shipton ML, Potter BVL, Hemmings AM, Brearley CA.   +6 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Bio-based trifunctional integration strategies for aquatic products during frozen storage: Synergistic mechanisms and perspectives. [PDF]

Food Chem X
Ma Y, Li Z, Chen R, Hu X, Yin X, Wang R, Ouyang D, Dan A.   +7 more
europepmc   +1 more source

Determination of phosphates using ion selective electrodes

This bachelor thesis is focused on the topic of determination of phosphates using ion-selective electrodes (ISE). Phosphates are essential for plants and animals.
Roglová, Valentina Růžena
core  

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Surfactant-coated iron oxide nanoparticles synthesized by coprecipitation as potential phosphate adsorbents in peritoneal dialysis. [PDF]

Nanoscale Adv
Lucante T, Carton A, Schmidt JN, Kiefer C, Choquet P, Zaloszyc A, Bégin-Colin S.   +6 more
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Nature Counts to Three: Universal Mg-Pinch Motif Polarizes the Cleaved Bond in NTP-Processing Enzymes. [PDF]

J Am Chem Soc
Dudas B, Berta D, Jambrina P, Buigues PJ, Suardiaz R, Gómez-Coca S, Deng W, Brooks BR, Vértessy BG, Rosta E.   +9 more
europepmc   +1 more source

Synthesis Methodology and Investigation of Calcium Phosphate Biomaterials for Bone Tissue Replacement in Regenerative Medicine

The wet chemical precipitation method was chosen for synthesis of calcium phosphates. It is one of the methods to obtain calcium phosphates that demonstrate both complexity of the method from point of view of physical chemistry and variability of product
Sokolova, Marina, Stīpniece, Līga, Borodajenko, Natālija, Šalma-Ancāne, Kristīne, Dubņika, Arita   +4 more
core