Results 251 to 260 of about 29,515 (273)
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Phosphatidic acid phosphatase in the erythrocyte membrane
Biochimica et Biophysica Acta, 1963A magnesium-dependent α-phosphatidic acid phosphatase is present in the erythrocyte membrane which is stimulated by sodium, and to a lesser extent by lithium, ammonium, potassium and rubidium. Cesium produces little or no stimulation. No magnesium-dependent, sodium-stimulated, activity was observed with β-phosphatidic acid or lysophosphatidic acid; but
Lowell E. Hokin +2 more
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Evidence for Phosphatidic Acid as the Sodium Carrier
Nature, 1959THE mechanism of active transport of ions is one of the basic problems of cell physiology. For example, most cells extrude sodium against a concentration gradient, and the system which brings this about has been termed the ‘sodium pump’. The biochemical mechanism of the ‘sodium pump’ has remained a mystery.
Lowell E. Hokin, Mabel R. Hokin
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Formation of phosphatidic acid in stressed mitochondria
Archives of Biochemistry and Biophysics, 2008Mitochondria are an important intracellular source of ROS as well as a sensitive target for oxidative damage under certain pathological conditions such as iron or copper overload. Mitochondrial membranes are rich in the tetraacyl phospholipid cardiolipin. Its integrity is important for efficient oxidative phosphorylation.
Franziska Stuckert +6 more
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Genetically Encoded Probes for Phosphatidic Acid
2012In addition to forming bilayers to separate cellular compartments, lipids participate in vesicular trafficking and signal transduction. Among others, phosphatidic acid (PA) is emerging as an important signaling molecule. The spatiotemporal distribution of cellular PA appears to be tightly regulated by localized synthesis and a rapid metabolism ...
Kassas, Nawal +6 more
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Metabolism of Phosphatidic Acid
1983In the first edition of the Handbook of Neurochemistry, Rossiter and Strickland1 reviewed the metabolism of phosphatidic acid in relation to the overall metabolism of phosphoglycerides, and Hawthorne and Kai2 described the metabolic relationship between phosphatidic acid and phosphoinositides.
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A procedure for the preparation of [32P]phosphatidic acid
Analytical Biochemistry, 1986The phosphorylation procedure of F. Cramer, W. Rittersdorf, and W. Bohm [(1961) Chem. Ber. 654, 180] using bis(triethylammonium) phosphate and trichloroacetonitrile was shown to be effective in the synthesis of [32P]phosphatidic acid. From diacylglyceride and 0.5 mCi H(3)32PO4, 25-50 microCi of labeled material (sp act = 1 mCi/mumol) can be prepared in
R K Keller, Nancy Cafmeyer, W L Adair
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Thyroid al Synthesis of Phosphatidic Acid
Endocrinology, 1968The enzymatic formation of phosphatidic acid from l-α-glycerophosphate and fatty acid was studied in cell free systems of calf and guinea pig thyroid. Phosphatidic acid formation was assayed by measuring the conversion of water-soluble l-α-glycerophosphate to the lipid which is extractable by organic solvents.
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Antibodies to liposomal phosphatidylserine and phosphatidic acid
Biochemistry and Cell Biology, 1990Polyclonal antisera to phosphatidylserine or phosphatidic acid were induced in rabbits by injecting liposomes containing phosphatidylserine or phosphatidic acid and lipid A. Adsorption of antisera with liposomes containing different phospholipids revealed that some degree of reactivity with one or more phospholipids other than the immunizing ...
Carl R. Alving, Benoy Banerji
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Phosphatidic acid- and phosphatidylserine-binding proteins
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006Phosphatidic acid and phosphatidylserine are negatively charged abundant phospholipids with well-recognized structural roles in cellular membranes. They are also signaling lipids since their regulated formation (or appearance) can constitute an important signal for downstream responses.
Nicholas T. Ktistakis, Catherine Stace
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Transport of phosphatidic acid within the mitochondrion
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990Transfer of phosphatidic acid from the outer to the inner membrane within intact rat liver mitochondria was assessed by measuring the ratio of lipid 32P to the marker enzyme of the outer membrane, rotenone-insensitive NADH-cytochrome c reductase, in the outer and inner membrane fractions obtained after incubation of mitochondria under conditions for ...
Józef Zborowski +2 more
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