Results 251 to 260 of about 30,263 (277)
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
1. The membrane-bound phosphatidate-dependent phosphatidic acid phosphatase activity of rat lung has been investigated in cytosol and microsomal fractions using as a substrate [32P]phosphatidate bound to heat inactivated rat liver microsomes. Both activities demonstrated broad pH optima with a maximum of 7.4--8 for the cytosol and a maximum of 6.5--7.5
Paul G. Casola, Fred Possmayer
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1. The membrane-bound phosphatidate-dependent phosphatidic acid phosphatase activity of rat lung has been investigated in cytosol and microsomal fractions using as a substrate [32P]phosphatidate bound to heat inactivated rat liver microsomes. Both activities demonstrated broad pH optima with a maximum of 7.4--8 for the cytosol and a maximum of 6.5--7.5
Paul G. Casola, Fred Possmayer
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Phosphatidic acids and derivatives VI: Phosphatidic acids derived from batyl alcohol [PDF]
Recueil des Travaux Chimiques des Pays-Bas, 1956 AbstractThe synthesis of a number of phosphatidic acids derived from batyl alcohol and of the two batyl alcohol phosphoric acids is described.Some properties of these substances are discussed.
P. E. Verkade, L. J. Stegerhoek
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Phosphatide acids and derivatives. VIII). Synthesis of monobenzyl esters of phosphatidic acids
Recueil des Travaux Chimiques des Pays-Bas, 1958AbstractThe preparation of dibenzyl esters of phosphatidic acids and their mono‐debenzylation by boiling with anhydrous sodium iodide in acetone solution is described.
P. E. Verkade +3 more
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Phosphatidic acids as intermediates in fatty acid absorption
Archives of Biochemistry and Biophysics, 1960Abstract Following the incubation of intestinal segments from the hamster in either palmitic acid-C 14 or NaH 2 P 32 O 4 , the phospholipid fraction containing the major activity is phosphatidic acids. The incorporation of P 32 into phosphatidic acids in the intestinal wall is increased two- to threefold when fatty acids are included in the ...
John M. Johnston, James H. Bearden
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Phosphatidic acid phosphatase in the erythrocyte membrane
Biochimica et Biophysica Acta, 1963A magnesium-dependent α-phosphatidic acid phosphatase is present in the erythrocyte membrane which is stimulated by sodium, and to a lesser extent by lithium, ammonium, potassium and rubidium. Cesium produces little or no stimulation. No magnesium-dependent, sodium-stimulated, activity was observed with β-phosphatidic acid or lysophosphatidic acid; but
Lowell E. Hokin +2 more
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Evidence for Phosphatidic Acid as the Sodium Carrier
Nature, 1959THE mechanism of active transport of ions is one of the basic problems of cell physiology. For example, most cells extrude sodium against a concentration gradient, and the system which brings this about has been termed the ‘sodium pump’. The biochemical mechanism of the ‘sodium pump’ has remained a mystery.
Lowell E. Hokin, Mabel R. Hokin
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Formation of phosphatidic acid in stressed mitochondria
Archives of Biochemistry and Biophysics, 2008Mitochondria are an important intracellular source of ROS as well as a sensitive target for oxidative damage under certain pathological conditions such as iron or copper overload. Mitochondrial membranes are rich in the tetraacyl phospholipid cardiolipin. Its integrity is important for efficient oxidative phosphorylation.
Franziska Stuckert +6 more
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Genetically Encoded Probes for Phosphatidic Acid
2012In addition to forming bilayers to separate cellular compartments, lipids participate in vesicular trafficking and signal transduction. Among others, phosphatidic acid (PA) is emerging as an important signaling molecule. The spatiotemporal distribution of cellular PA appears to be tightly regulated by localized synthesis and a rapid metabolism ...
Kassas, Nawal +6 more
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Metabolism of Phosphatidic Acid
1983In the first edition of the Handbook of Neurochemistry, Rossiter and Strickland1 reviewed the metabolism of phosphatidic acid in relation to the overall metabolism of phosphoglycerides, and Hawthorne and Kai2 described the metabolic relationship between phosphatidic acid and phosphoinositides.
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A procedure for the preparation of [32P]phosphatidic acid
Analytical Biochemistry, 1986The phosphorylation procedure of F. Cramer, W. Rittersdorf, and W. Bohm [(1961) Chem. Ber. 654, 180] using bis(triethylammonium) phosphate and trichloroacetonitrile was shown to be effective in the synthesis of [32P]phosphatidic acid. From diacylglyceride and 0.5 mCi H(3)32PO4, 25-50 microCi of labeled material (sp act = 1 mCi/mumol) can be prepared in
R K Keller, Nancy Cafmeyer, W L Adair
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