Results 41 to 50 of about 4,841 (163)
Brain Pathology, Volume 36, Issue 1, January 2026.Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li +7 more
wiley +1 more source
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation [PDF]
, 2013 Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to be metabolized of which the ...
Tillander, Veronika
core +1 more source
New Phytologist, Volume 249, Issue 2, Page 892-916, January 2026.Summary Plant lipid droplets (LDs) and their associated proteins have numerous subcellular and physiological functions. While considerable progress has been made for LDs in many tissues, the function and composition of LDs in roots remain largely unexplored.
Patricia Scholz +22 more
wiley +1 more source
Potential of CRISPR/Cas9 Genome Engineering for Biofuel Production From Economically Relevant Algae
International Journal of Energy Research, Volume 2026, Issue 1, 2026.The worldwide energy demand continues to rise, while reliance on fossil fuels remains unsustainable due to global warming, declining reserves and rising oil prices. This has intensified the search for renewable alternatives. Among these, microscopic algae have emerged as a promising feedstock for third‐generation biofuels.
Sundram Kumari +6 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, Volume 599, Issue 24, Page 3569-3590, December 2025.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes [PDF]
, 2017 Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease.
Belloso Uribe, Kepa +4 more
core +2 more sources
iMetaOmics, Volume 2, Issue 4, December 2025.Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen +7 more
wiley +1 more source
Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]
, 2020 BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O +2 more
core +1 more source
Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family [PDF]
, 2013 Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship.
Afonso de Menezes, Claudia Beatriz +39 more
core +6 more sources