Results 41 to 50 of about 4,396 (136)
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, Volume 599, Issue 24, Page 3569-3590, December 2025.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Photo-damage, photo-protection and age-related macular degeneration [PDF]
, 2015 Age-related macular degeneration (AMD) is a degenerative retinal disease that causes blindness in people 60-65 years and older, with the highest prevalence appearing in people 90 years-old or more.
Marquioni Ramella, Melisa Daniela +1 more
core +1 more source
iMetaOmics, Volume 2, Issue 4, December 2025.Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen +7 more
wiley +1 more source
Sterol-binding proteins in late endosomes : Regulation of endosome motility and lipid metabolism [PDF]
, 2011 Despite its bad reputation in the mass media, cholesterol is an indispensable constituent of cellular membranes and vertebrate life. It is, however, also potentially lethal as it may accumulate in the arterial intima causing atherosclerosis or elsewhere ...
Uronen, Riikka-Liisa
core
Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. [PDF]
, 2016 Sleep loss and insufficient sleep are risk factors for cardiometabolic diseases, but data on how insufficient sleep contributes to these diseases are scarce.
Aho, Vilma +2 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]
, 2020 BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O +2 more
core +1 more source
British Journal of Haematology, Volume 208, Issue 2, Page 763-768, February 2026.
Eleonora Camilleri +8 more
wiley +1 more source
Método para reconstrução in silico de redes metabólicas de fungos : um estudo de caso para o Paracoccidioides lutzii [PDF]
, 2014 Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Exatas, Departamento de Ciência da Computação, 2014.Os fungos produzem uma variedade de metabólitos com aplicações na indústria e na medicina, ao mesmo tempo que podem ser patógenos ...
Silva, Waldeyr Mendes Cordeiro da
core
Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes [PDF]
, 2017 Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease.
Belloso Uribe, Kepa +4 more
core +3 more sources