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Biosynthesis of phosphatidylcholine in bacteria

Progress in Lipid Research, 2003
Phosphatidylcholine (PC) is the major membrane-forming phospholipid in eukaryotes and can be synthesized by either of two pathways, the methylation pathway or the CDP-choline pathway. Many prokaryotes lack PC, but it can be found in significant amounts in membranes of rather diverse bacteria and based on genomic data, we estimate that more than 10% of ...
Christian Sohlenkamp   +2 more
openaire   +2 more sources

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.

Journal of Proteome Research, 2017
We undertook an unbiased metabolite profiling of fibroblasts from schizophrenia patients and healthy controls to identify metabolites and pathways that are dysregulated in disease, seeking to gain new insights into the disease biology of schizophrenia ...
Joanne H. Huang   +9 more
semanticscholar   +1 more source

Autoxidation of phosphatidylcholine liposomes

Lipids, 1982
AbstractAutoxidation of pure soybean phosphatidylcholine liposomes at 40 C was found to proceed without an observed induction period, but otherwise, the rates of disappearance of the linoleic acid (70% of total) and linolenic acid (6% of total) followed typical autocatalytic kinetics.
Guey-Shuang Wu   +2 more
openaire   +3 more sources

The binding of phosphatidylcholine to the phosphatidylcholine transfer protein: affinity and role in folding

Chemistry and Physics of Lipids, 2001
Bovine liver phosphatidylcholine transfer protein (PC-TP) has been expressed in Escherichia coli and purified to homogeneity from the cytosol fraction at a yield of 0.45 mg PC-TP per 10 mg total cytosolic protein. In addition, active PC-TP was obtained from inclusion bodies.
A.P.M. de Brouwer   +8 more
openaire   +4 more sources

Measurement of Lung Phosphatidylcholines in Exhaled Breath Particles by a Convenient Collection Procedure.

Analytical Chemistry, 2015
An analytical method based on high-performance liquid chromatography coupled to quadrupole tandem mass spectrometry was developed for the quantitative determination of four phosphatidylcholines (PCs) in human exhaled breath particles.
S. Ullah, S. Sandqvist, O. Beck
semanticscholar   +1 more source

Thermodynamics of mixing of dipalmitoyl phosphatidylcholine and egg phosphatidylcholine in hydrated bilayers

Canadian Journal of Biochemistry, 1982
Dipalmitoyl phosphatidylcholine (DPPC) and egg phosphatidylcholine (egg PC) are not completely miscible at all temperatures. Their phase diagram was determined by differential scanning calorimetry (DSC) of aqueous mixtures of the two. From the integrated DSC curves we obtained the enthalpy of solution of DPPC in egg PC, Δhs, as a function of the mole ...
David O. Tinker, Rosita Low
openaire   +3 more sources

The solubilisation of some steroids by phosphatidylcholine and phosphatidylcholine-cholesterol vesicles

Chemistry and Physics of Lipids, 1979
The solubility of the three steroid hormones, progesterone, testosterone, and estradiol-17 beta in water and phosphatidylcholine vesicles was measured after shaking and ultrasonication. All three steroids have low water solubility, which increases considerably at sonication for testosterone and estradiol-17 beta. The phosphatidylcholine vesicles have a
openaire   +3 more sources

The structures of bile phosphatidylcholines

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
Abstract Phosphatidylcholines from the bile of pigs, sheep and cows were isolated and the fatty acid composition of each determined. Linoleic acid was the principal poly-unsaturated fatty acid of pig bile phosphatidylcholine but that from the ruminants contained appreciable amounts of 9-cis, 11-trans-octadecadienoic acid, 9-cis, 11 -trans, 15-cis ...
openaire   +3 more sources

Synthesis of a photocleavable bola-phosphatidylcholine

Bioorganic & Medicinal Chemistry, 2023
Phosphatidylinositol transfer proteins (PITPs) are ubiquitous in eukaryotes and are involved in the regulation of phospholipid metabolism, membrane trafficking, and signal transduction. Sec14 is a yeast PITP that has been shown to transfer phosphatidylinositol (PI) or phosphatidylcholine (PC) from the endoplasmic reticulum to the Golgi.
Sean Wilson   +6 more
openaire   +2 more sources

Influence of dicarboxylic phosphatidylcholines on the stability and phase transition of phosphatidylcholine liposomes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981
The effect of dicarboxylic phosphatidylcholines (glutaryl phosphatidylcholine) on the stability and phase transition of phosphatidylcholine liposomes is examined by using liposomes prepared with egg phosphatidylcholine or dipalmitoyl phosphatidylcholine and by varying the surface charge by addition of dicetyl phosphate.
Louis Douste-Blazy   +2 more
openaire   +3 more sources

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