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In vitro glycation and glycoxidation of phosphatidylethanolamines

Free Radical Biology and Medicine, 2014
Formation and accumulation of advanced glycation end products (AGEs) appear to correlate with many human diseases, such as atherosclerosis and inflammation. Whereas AGE-modified proteins relatively well studied, aminophospholipid AGE-adducts have been less intensively investigated.
Andrea, Annibal   +3 more
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The Equilibria of Phosphatidylethanolamine-Cholesterol and Phosphatidylcholine–Phosphatidylethanolamine in Monolayers at the Air/Water Interface

Journal of Macromolecular Science, Part A, 2009
Monolayers of phosphatidylethanolamine (PE), cholesterol (Ch), phosphatidylcholine (PC), and binary mixtures (PC-PE or PE-Ch) were investigated at the air/water interface. The surface tension values of pure and mixed monolayers were used to calculate π -A isotherms.
Aneta D. Petelska   +1 more
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Labeling Membranes with Fluorescent Phosphatidylethanolamine

Cold Spring Harbor Protocols, 2011
INTRODUCTIONThe phospholipid phosphatidylethanolamine (PE) can be conjugated via its head group to a number of fluorophores, including rhodamine, BODIPY (boron-dipyrromethene; 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene), and NBD (N-(7-nitrobenz-2-oxa-1,3-diazole-4-yl)).
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Influence of retinoids on phosphatidylethanolamine lipid polymorphism

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1992
The interaction of all-trans-retinoic acid and all-trans-retinol with dielaidoylphosphatidylethanolamine has been studied by differential scanning calorimetry and 31P-NMR spectroscopy. Increasing concentrations of all-trans-retinoic acid up to a mol fraction of 0.09 were found to induce shifts to lower temperatures of both the L beta to L alpha and L ...
A, Ortiz   +3 more
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Synthesis of radio-isotopically labelled phosphatidylethanolamines

Chemistry and Physics of Lipids, 1974
Abstract The total chemical synthesis of di and tri-radioisotopically labelled 1–2 dipalmitoyl-sn-glycero-3-phosphorylethanolamine (PE) labelled with 14C-(diacyl) and 32P and 14C-(diacyl), 32P and 3H-(ethanolamine) are described. Due to the short half-life of the 32P isotope in the time consuming synthesis of the intramolecularly tri-labelled ...
J D, Billimoria, J S, Owen, G H, Scott
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The possible functional significance of phosphatidylethanolamine methylation

Nature, 1980
The conversion of phosphatidylethanolamine to phosphatidylcholine was first reported in rat liver microsomes by Bremer and Greenberg. The reaction requires three successive methylations of the ethanolamine moiety by S-adenosylmethionine. The highest activity for this enzyme has been found in liver microsomes and the enzyme from rat liver was recently ...
D E, Vance, B, de Kruijff
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Phosphatidylethanolamine N-methyltransferase from liver

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997
Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Most PEMT activity (PEMT1) is associated with endoplasmic reticulum. A second form of the enzyme (PEMT2) has been localized to the mitochondria-associated membrane. PEMT2 is a 22.5-kDa protein that has been purified from rat liver.
D E, Vance, C J, Walkey, Z, Cui
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Studies on the thermotropic behavior of aqueous phosphatidylethanolamines

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1983
The thermal response of aqueous dispersions of a series of synthetic saturated phosphatidylethanolamines was studied by differential scanning calorimetry and by infrared spectroscopy. Dispersions which had not been previously heated above tm, the temperature of the gel to liquid crystalline transition, showed transitions at a higher temperature, tm+h ...
Mantsch, H. H.   +3 more
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Extended hydrogen-bonded structures of phosphatidylethanolamine

Chemistry and Physics of Lipids, 1988
The structure of phosphatidylethanolamine in pure dry hexane was studied. Viscosity measurements show that the hexane solution of PE has a very high viscosity, while freeze fracture electron microscopy revealed extensive fibre-like structures. These extended structures are disrupted by the addition of small amounts of water or organic solvents which ...
Sen, Arindam   +3 more
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Stabilization of phosphatidylethanolamine hydroperoxides in human plasma

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1989
When phosphatidylcholine hydroperoxides (PC-OOH) and phosphatidylethanolamine hydroperoxides (PE-OOH) were incubated in normal saline at 37 degrees C, PE-OOH were decomposed more rapidly than PC-OOH, possibly due to Fe2+-binding ability of their polar head-group. In human plasma, both phospholipid hydroperoxides were stable during incubation.
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