Light Quantity Impacts Early Response to Cold and Cold Acclimation in Young Leaves of Arabidopsis
ABSTRACT Plant reactions to stress vary with development stage and fitness. This study assessed the relationship between light and chilling stress in Arabidopsis acclimation. By analysing the transcriptome and proteome responses of expanding leaves subjected to varying light intensity and cold, 2251 and 2064 early response genes and proteins were ...
Markéta Luklová+14 more
wiley +1 more source
PI3KC2β depletion rescues endosomal trafficking defects in Mtm1 knockout skeletal muscle cells. [PDF]
Mansat M+5 more
europepmc +1 more source
KirBac1.1: It\u27s an inward rectifying potassium channel [PDF]
Cheng, Wayland W.L.+2 more
core +1 more source
DDR2‐mediated autophagy inhibition contributes to angiotensin II‐induced adventitial remodeling
Ddr2 promotes PI3K/Akt/mTOR mediated autophagy inhibition, which contributes to Ang II‐induced AF phenotypic switch. Abstract Aims Adventitial remodelling in hypertension is characterized by a transformation of adventitial fibroblasts (AFs) into myofibroblasts.
Gaojian Huang+7 more
wiley +1 more source
The Essentiality of Amino Acids in Healthiness and Disease State: Type II Diabetes as a Case Study
This review investigates the functions of amino acids in normal physiological states, their potential as a diagnostic biomarker, the probable risk of deficiency, and the therapeutic ability for managing and preventing type 2 diabetes mellitus. ABSTRACT A healthy life depends on the availability and the synthesis of amino acids as they are building ...
Samuel Idowu Fayomi+2 more
wiley +1 more source
Towards Improved Bioavailability of Cereal Inositol Phosphates, <i>Myo</i>-Inositol and Phenolic Acids. [PDF]
Żyła K, Duda A.
europepmc +1 more source
Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar+13 more
wiley +1 more source
A three-way organelle junction controls PI(4)P metabolism and mitochondrial division. [PDF]
Posor Y, Haucke V.
europepmc +1 more source
Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen+6 more
wiley +1 more source