Results 291 to 300 of about 19,012 (341)

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann   +2 more
wiley   +1 more source

Dexmedetomidine Reduces Chronic Stress–Related Thrombosis in a Mouse FeCl3 Model

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Schematic summary of the mechanism by which dexmedetomidine prevents chronic stress–related carotid artery thrombosis in a mouse FeCl3 model. These findings present evidence and a potential mechanistic explanation of the Dex‐mediated amelioration of arterial thrombosis associated with the reduction of oxidative stress, inflammation, and apoptosis, and ...
Huazhen Wang   +11 more
wiley   +1 more source

Impact of ERG6 Gene Deletion on Membrane Composition and Properties in the Pathogenic Yeast Candida glabrata. [PDF]

open access: yesCell Biochem Biophys
Jacko J   +8 more
europepmc   +1 more source

Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors. [PDF]

open access: yesJ Biol Chem
Ng MY   +12 more
europepmc   +1 more source

Role of PI3 Kinases in Cell Signaling and Soleus Muscle Atrophy During Three Days of Unloading. [PDF]

open access: yesInt J Mol Sci
Zaripova KA   +4 more
europepmc   +1 more source

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