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The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu   +5 more
wiley   +1 more source

Metabolomics of Papanicolaou Tests for the Discovery of Ovarian Cancer Biomarkers. [PDF]

open access: yesMetabolites
Sah S   +7 more
europepmc   +1 more source

Circulating Erythrocyte- and Endothelial-Derived Microvesicles as Biomarkers of Hemolysis and Clinical Severity in Sickle Cell Disease. [PDF]

open access: yesJ Cell Mol Med
Khalfaoui K   +12 more
europepmc   +1 more source

Immune cell activation produces locally scrambled foci of plasma membrane lipids.

open access: yesFaraday Discuss
Sputay D   +7 more
europepmc   +1 more source
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Phosphatidylserine-mediated oral tolerance

Cellular Immunology, 2023
Phosphatidylserine (PS) is an anionic phospholipid exposed on the surface of apoptotic cells. The exposure of PS typically recruits and signals phagocytes to engulf and silently clear these dying cells to maintain tolerance via immunological ignorance.
Nhan H, Nguyen   +4 more
openaire   +2 more sources

Phosphatidylserine in Diabetes Research

Molecular Pharmaceutics, 2022
Phospholipids are lipids that constitute the basic structure of cell membranes. In-depth research has shown that in addition to supporting cell structures, phospholipids participate in multiple cellular processes, including promoting cell signal transduction, guiding protein translocation, activating enzymatic activity, and eliminating dysfunctional ...
Dandan Xiao, Wenguang Chang
openaire   +2 more sources

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