Results 181 to 190 of about 2,974,682 (398)

Caesalpinia sappan L. Wood is a Potential Source of Natural Phosphodiesterase-1 Inhibitors [PDF]

, 2020
Nanang Fakhrudin, Arief Nurrochmad, Bambang Sudarmanto, Zullies Ikawati, Zullies Ikawati   +4 more
openalex   +1 more source

Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti‐inflammatory effects in mdx mice with Duchenne muscular dystrophy

The FASEB Journal, 2017
Yasunori Nio, Masayuki Tanaka, Yoshihiko Hirozane, Yo Muraki, Mitsugi Okawara, M. Hazama, T. Matsuo   +6 more
semanticscholar   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults.

Journal of American Academy of Dermatology, 2016
A. Paller, W. Tom, M. Lebwohl, R. Blumenthal, M. Boguniewicz, R. Call, L. Eichenfield, D. Forsha, W. Rees, E. Simpson, M. Spellman, L. S. Stein Gold, A. Zaenglein, Matilda H. Hughes, L. Zane, A. Hebert   +15 more
semanticscholar   +1 more source

Treatment Satisfaction, Efficacy, and Safety of Delgocitinib Ointment Following Switch From Topical Corticosteroids for Trunk and Extremity Rash in Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent remissions and relapses. Topical anti‐inflammatory steroids are commonly used for treatment, but their long‐term use poses concerns because of potential side effects. Delgocitinib ointment, a Janus kinase inhibitor, has demonstrated efficacy in several clinical
Masatoshi Abe, Atsuyuki Igarashi, Hiroyuki Kitajima, Hiroyuki Toyama, Kenji Kabashima, Hidehisa Saeki   +5 more
wiley   +1 more source

Treatment Patterns and Healthcare Utilization on Pediatric Atopic Dermatitis With Allergic Comorbidities: A Japanese Claims‐Based Study

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic, itchy skin disease that often begins in infancy and may persist into adulthood. The high co‐occurrence of allergic comorbidities (ACMs; asthma, food allergy, and allergic rhinitis) makes it a growing public health concern.
Masaki Futamura, Yumi Kang, Ambrish Singh, Junichi Danjo, Takashi Matsuo, Hitoe Torisu‐Itakura, Mizuho Nagao   +6 more
wiley   +1 more source

THU0097 Phosphodiesterases 4 (PDE4) inhibitor ameliorates experimental arthritis [PDF]

, 2018
W. Chen, Zhenjian Xu, Hwabok Wee, Gregory S. Lewis, Nancy J. Olsen, Jin Lin, Songguo Zheng   +6 more
openalex   +1 more source

Metabolic products of microorganisms. 268. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. II. Minor components belonging to the obscurolide B to D series.

, 1993
M. RITZAU, SIEGRID PHILIPPS, Axel Zeeck, HUBERT HOFF, Hans Zähner   +4 more
openalex   +2 more sources

The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females [PDF]

, 2012
Giuseppe Murdolo, Mikaela Sjöstrand, Lena Strindberg, Peter Lönnroth, Per‐Anders Jansson   +4 more
openalex   +1 more source

Substance Use and Sex Index version 2 (SUSI‐2): Validation of a brief questionnaire for the measurement of behaviours associated with transmission of blood borne viruses and sexually transmitted infections

Addiction, EarlyView.
Abstract Aims This study sought to validate a community‐acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood‐borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual ...
Brendan Clifford, Raimondo Bruno, Liam Acheson, Michael E. Cecilio, Krista J. Siefried, Jack Freestone, Vincent J. Cornelisse, Brendan Crozier, Nicky Bath, Nadine Ezard   +9 more
wiley   +1 more source