Results 91 to 100 of about 20,352 (205)
VIEW, EarlyView.A high‐glucose environment induced an imbalance in mitochondrial homeostasis, which resulted in the inhibition of bone tissue regeneration. In this study, we first introduce the exogenous noninvasive direct current electric field (DCEF) strategy for regulating mitochondrial homeostasis and explore its effect on bone regeneration in high‐glucose ...
Dongzong Huang +14 more
wiley +1 more source
Yeast V-ATPase Regulation by Phosphofructokinase-1 [PDF]
, 2015 V-ATPase is a vacuolar (lysosome-like) ATPase-dependent proton pump necessary for maintaining pH homeostasis in the organelles of the endomembrane system. It also contributes to regulation of the cytosol pH and the extracellular pH. In specialized cells (
Chan, Chun-Yuan
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A quantitative screen for metabolic enzyme structures reveals patterns of assembly across the yeast metabolic network. [PDF]
, 2019 Despite the proliferation of proteins that can form filaments or phase-separated condensates, it remains unclear how this behavior is distributed over biological networks. We have found that 60 of the 440 yeast metabolic enzymes robustly form structures,
Begovich, Kyle +5 more
core +3 more sources
Insect Science, EarlyView.Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido +4 more
wiley +1 more source
Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. [PDF]
, 2019 Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like ...
de Oliveira, Patricia Gnieslaw +4 more
core +1 more source
Modeling cancer metabolism on a genome scale [PDF]
, 2015 Cancer cells have fundamentally altered cellular metabolism that is associated with their tumorigenicity and malignancy. In addition to the widely studied Warburg effect, several new key metabolic alterations in cancer have been established over the last
Barbara Chaneton +8 more
core +1 more source
Journal of Diabetes Investigation, EarlyView.Insulin resistance in muscle mainly disrupts non‐canonical insulin signaling pathways. Exercise‐induced MINDY1 S441 phosphorylation improves insulin sensitivity, highlighting its potential role in mediating exercise benefits in metabolic disease.
Shun Masuda, Takashi Matsuzaka
wiley +1 more source
Plant Biotechnology Journal, EarlyView.Summary The cell death‐inducing DNA fragmentation factor alpha (DFFA)‐like effectors (CIDEs), including CIDEA, CIDEB and CIDEC, regulate the number and size of lipid droplets (LDs) in vertebrates. However, no homologue of CIDE has been reported in plants.
Yao Xiong +5 more
wiley +1 more source
PFK-1 Transcript Amounts in the Liver and Skeletal Muscle of Pigeons and Quail Acutely Exposed to High Embryonic Incubation Temperatures [PDF]
, 2018 The developing avian embryo is reliant on external sources of heat. Incubation temperatures above or below optimal alter development and metabolic function, and may compromise emergence and post-hatch adaptation.
Loveless, Michael
core
Metabolic plasticity of tumor cell mitochondria [PDF]
, 2018 open5noMitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell.
core +1 more source