Results 81 to 90 of about 144,128 (376)
Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2
Toxins, 2021 Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve ...
Caterina Peggion, Fiorella Tonello
doaj +1 more source
Acid phospholipase A activities in rat hepatocytes [PDF]
, 1988 Cultured rat hepatocytes exhibit acid phospholipase A activity. On the basis of product formation from stereospecifically radiolabeled phosphatidylethanolamine substrates, phospholipases A1 and A2 have been identified with optimal activities at pH 4.5 ...
Kunze, Hans +2 more
core +1 more source
Toxins, 2013 Neuro- and myotoxicological signs and symptoms are significant clinical features of envenoming snakebites in many parts of the world. The toxins primarily responsible for the neuro and myotoxicity fall into one of two categories—those that bind to and ...
J. Harris, T. Scott-Davey
semanticscholar +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
FEBS Open Bio, EarlyView.The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi +2 more
wiley +1 more source
Hepatology Communications, EarlyView., 2022 Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk +6 more
wiley +1 more source
METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]
, 2000 The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core +1 more source
Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency [PDF]
, 2018 BackgroundHereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that
Andrea Zanichelli +16 more
core +3 more sources
International Journal of Molecular Sciences, 2013 The present review aims to systematically and critically analyze the current knowledge on phospholipases and their role in physiological and pathological mineralization undertaken by mineralization competent cells.
S. Mebarek +6 more
semanticscholar +1 more source
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Advanced Functional Materials, EarlyView.Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu +6 more
wiley +1 more source
Bacterial phospholipases C with dual activity: phosphatidylcholinesterase and sphingomyelinase
FEBS Open Bio, 2021 Bacterial phospholipases and sphingomyelinases are lipolytic esterases that are structurally and evolutionarily heterogeneous. These enzymes play crucial roles as virulence factors in several human and animal infectious diseases.
Laura Monturiol‐Gross +3 more
doaj +1 more source