Results 281 to 290 of about 532,032 (389)

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Hydroxychloroquine-Induced Renal Phospholipidosis. [PDF]

Cureus
Hafeez K, Baker S, Shori SK, Acharya S, Gautam S.   +4 more
europepmc   +1 more source

Surface potentials and electric dipole moments of ganglioside and phospholipid monolayers: contribution of the polar headgroup at the water/lipid interface

, 1989
Heinz Beitinger, Viola Vogel, Dietmar Möbius, H. Rahmann   +3 more
openalex   +2 more sources

Generation and Biological Activities of Oxidized Phospholipids

Antioxidants and Redox Signaling, 2010
V. Bochkov, O. Oskolkova, K. Birukov, A. Levonen, C. Binder, J. Stöckl   +5 more
semanticscholar   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Arabidopsis phospholipid modifications mediate cellulase-induced resistance to a fungal peptide antibiotic by imposing cell polarity. [PDF]

New Phytol
Panthapulakkal Narayanan S, Dotson BR, Noack L, Holla S, Ren S, Dörmann P, Widell S, Persson S, Lager I, Rasmusson AG.   +9 more
europepmc   +1 more source

Effect of SAM-Dependent Methyltransferases from Halomonas sp. YLGW01 on Phospholipid Fatty Acids Composition and Production of Polyhydroxalkanoates in Escherichia coli

Tae‐Rim Choi, Gaeun Lim, Ye Sun Han, Jong‐Min Jeon, Jeonghee Yun, Jeong‐Jun Yoon, Shashi Kant Bhatia, Yung-Hun Yang   +7 more
openalex   +2 more sources

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Characterization and application of lecithin powders from sunflower and peanut to enhance oil stability in peanut butter. [PDF]

Food Chem X
Ibrahim MMS, Elkhedir A, Shakak MAS, Alagib AA.   +3 more
europepmc   +1 more source

Drosophila models uncover substrate channeling effects on phospholipids and sphingolipids in peroxisomal biogenesis disorders

Michael F. Wangler, Yu-Hsin Chao, Mary R. Roth, Ruth Welti, James A. McNew   +4 more
openalex   +1 more source