Results 291 to 300 of about 370,671 (342)

A Single‐Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration

Advanced Science, EarlyView.
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao, Wen‐Bo Li, Na‐Na Chen, Yang Yi, Ze‐Han Wang, Xian Chen, Yang‐Yang Zhao, Ze‐Li Yuan, Jie Gao, Yu‐Chen Pan, Dong‐Sheng Guo, Qi‐Hai Gong   +11 more
wiley   +1 more source

Lipid Composition Analysis of Cricket Oil from Crickets Fed with Broken Rice-Derived Bran. [PDF]

Insects
Sogame R, Miyazawa T, Toda M, Iijima A, Bhaswant M, Miyazawa T.   +5 more
europepmc   +1 more source

Root Meristem Maintenance Mechanisms are Key to Plant Defense Against Nanoplastics

Advanced Science, EarlyView.
Small nanoplastics can disrupt cell integrity and inhibit cell division in meristem zone of plant root. The plants can counteract the cell damage by upregulating genes associated with root meristem maintenance and increasing auxin accumulation by PIN2 transport inhibition.
Sirui Ma, Zhengdong Hua, Chenglong Tang, Xinran Qiu, Ling Ding, Xujun Liang, Yuzhou Zhang, Xuetao Guo   +7 more
wiley   +1 more source

Lipid metabolism in the adrenal gland. [PDF]

Front Endocrinol (Lausanne)
Aderhold A, Alexaki VI.
europepmc   +1 more source

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

Advanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park, Min‐Ji Kim, Jae‐Ho Shin, Eunsoo Kim, Myeongjoo Son, Seungjun Lee   +5 more
wiley   +1 more source

The Utility of Fourier Transform Infrared Spectroscopy (FTIR) for Detecting Exercise-Induced Changes in the Human Hand Epidermis. [PDF]

J Biophotonics
Król P, Obmiński Z, Reich A, Czarny W, Cebulski J, Depciuch J, Zamorski M, Stępień K, Rydzik Ł.   +8 more
europepmc   +1 more source

Unlocking Cryogenic Self‐Assembly of Lyotropic Liquid Crystals: A Molecular Perspective From Short‐Range to Long‐Range Scales

Advanced Science, EarlyView.
Cryogenic self‐assembly of lyotropic liquid crystals is achieved using alkyl alkanolamide amphiphiles in a 1,2‐propanediol/water cosolvent system. The hydrocarbon chain length significantly affects the molecular arrangement in bilayers and their long‐range orientational ordering.
Weiluo Guo, Zhenghua Sun, Runxi Wang, Zhuo Zheng, Yubin Ke, Hua Yang, Lingzhi Xie, Yujun Feng, Hongyao Yin   +8 more
wiley   +1 more source

Lipid Signature of Motile Human Sperm: Characterization of Sphingomyelin, Ceramide, and Phospholipids with a Focus on Very Long Chain Polyunsaturated Fatty Acids. [PDF]

Int J Mol Sci
Oresti GM, Luquez JM, Belmonte SA.
europepmc   +1 more source

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

Advanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +5 more
wiley   +1 more source

Choline alphoscerate: insights between acquired certainties and future perspectives. [PDF]

Front Aging Neurosci
Biggio G, Mencacci C.
europepmc   +1 more source