Results 31 to 40 of about 18,546 (204)
Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1
Frontiers in Chemistry, 2022 Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs stalled type I topoisomerase (TOP1)-DNA complexes by hydrolyzing the phosphodiester bond between the TOP1 Y723 residue and the 3′-phosphate of its DNA substrate.
Xue Zhi Zhao +6 more
doaj +1 more source
Platinum(II) phosphonate complexes derived from endo-8-camphanylphosphonic acid [PDF]
, 2011 The reactions of cis-[PtCl₂L₂] [L = PPh₃, PMe₂Ph or L₂ = Ph₂P(CH₂)₂PPh₂ (dppe)] with endo-8-camphanylphosphonic acid (CamPO₃H₂) and Ag₂O in refluxing dichloromethane gave platinum(II) phosphonate complexes [Pt(O₃PCam)L₂].
Fortney-Zirker, Ryland G. +6 more
core +2 more sources
The McKenna reaction – avoiding side reactions in phosphonate deprotection
Beilstein Journal of Organic Chemistry, 2020 The McKenna reaction is a well-known and popular method for the efficient and mild synthesis of organophosphorus acids. Bromotrimethylsilane (BTMS) is the main reagent in this reaction, which transforms dialkyl phosphonate esters into bis(trimethylsilyl ...
Katarzyna Justyna +4 more
doaj +1 more source
Spectroscopic and Theoretical Study of the Grafting Modes of Phosphonic Acids on ZnO Nanorods [PDF]
, 2013 Metal oxides are versatile substrates for the design of a wide range of SAM-based organic-inorganic materials among which ZnO nanostructures modified with phosphonic SAM are promising semiconducting systems for applications in technological fields such ...
ALEEVA, Yana +4 more
core +1 more source
Molecules, 2019 Phosphonic acids, aminophosphonic acids, and phosphonocarboxylic acids are characterized by an advanced hyphenated technique, combining potentiometric titration with NMR spectroscopy.
Gerhard Hägele
doaj +1 more source
Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues [PDF]
, 2007 Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate ( DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids ...
Devreux, Vincent +5 more
core +2 more sources
Solids, 2023 Stearic and phenyl-phosphonic acids were applied to fine aluminum particles to understand their effect on the surface chemical composition and bulk properties of the surface-treated powders.
Bellamarie Ludwig
doaj +1 more source
Corrosion processes controlled by phosphonic acid nano-layers [PDF]
, 2016 Self assembled monolayers (SAM) formed by fluoro-phosphonic and undecenyl-phosphonic acids on carbon steel surfaces as anticorrosive nanocoatings were investigated.
Abohalkuma, Talah +2 more
core +2 more sources
Molecules, 2022 All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained.
Liwia Lebelt +2 more
doaj +1 more source
Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design. [PDF]
, 2011 The relaxed complex scheme, a virtual-screening methodology that accounts for protein receptor flexibility, was used to identify a low-micromolar, non-bisphosphonate inhibitor of farnesyl diphosphate synthase.
Cao, Rong +7 more
core +2 more sources