Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani +6 more
wiley +1 more source
Autism spectrum disorder is a complex neurological and developmental disorder that is characterized by altered brain structures and interconnectivity, which results in a vast array of psychosocial and physiological irregularities. This is due to the complex genetic topography of autism and to the intersectionality of genetic and environmental factors ...
Rachel A. Hellmann Whitaker +9 more
wiley +1 more source
How do roots respond to osmotic stress? A transcriptomic approach to address this question in a non-model crop [PDF]
Drought is a complex phenomenon that is relevant for many crops. Performing high-throughput transcriptomics in non-model crops is challenging. The non-model crop where our workflow has been tested on is banana (Musa spp.), which ranks among the top ten ...
Carpentier, Sebastien C. +6 more
core
Biofilm and planktonic pneumococci demonstrate disparate immunoreactivity to human convalescent sera [PDF]
Background Streptococcus pneumoniae (the pneumococcus) is the leading cause of otitis media, community-acquired pneumonia (CAP), sepsis, and meningitis. It is now evident that S.
Carlos J Sanchez +5 more
core +2 more sources
Objective To investigate the relationship between neuron-specific enolase (NSE) levels in serum and cerebrospinal fluid (CSF) of patients with acute traumatic brain injury (TBI) and the prognosis of TBI patients.
Yun-yang LIU +3 more
doaj
Objective To analyze the influencing factors of acute kidney injury (AKI) after surgery in spontaneous intracranial hemorrhage (sICH). Methods A total of 151 patients with sICH who underwent surgery in Tianjin Huanhu Hospital from March 2023 to June ...
ZHANG Lei +4 more
doaj +1 more source
Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus [PDF]
The range of exoproteins and core exoproteome of 14 Staphylococcus aureus isolates representing major lineages associated with asymptomatic carriage and clinical disease in the UK was identified by MS proteomics using a combined database incorporating ...
Edwards, R.J. +9 more
core +4 more sources
Comprehensive Pan‐Cancer Analysis of TRNT1 as a Potential Biomarker for Breast Cancer
ABSTRACT TRNT1, an RNA nucleotide transferase, plays a critical role in cellular processes and may be involved in cancer. However, its role in cancer has not been fully explored. This study aims to explore the potential significance of TRNT1 in cancer, particularly in breast cancer (BC) progression and prognosis.
Xinwei Li, Yue Meng, Bing Gu
wiley +1 more source
Research of the serum level of neuron⁃specific enolase in children with various types of seizure
Objective To explore the relevance between the level changes of serum neuron⁃specific enolase (NSE) and neuronal damage in various seizure types of children with epilepsy.
Chun WANG +3 more
doaj
Construction and validation of a first-generation Bordetella bronchiseptica long-oligonucleotide microarray by transcriptional profiling the Bvg regulon [PDF]
Background Bordetella bronchiseptica is a bacterial respiratory pathogen that infects a broad range of mammals, causing chronic and often subclinical infections.
Tracy L Nicholson
core +1 more source

