Results 41 to 50 of about 2,732 (110)

Transcriptomic and Metabolomic Insights Into the Prebiotic Potential of Camellia Seed Oil for Enhancing Akkermansia muciniphila Proliferation In Vitro

Food Science &Nutrition, Volume 13, Issue 1, January 2025.
Camellia seed oil is rich in bioactive compounds, which could promote the in vitro proliferation of Akkermansia muciniphila by reducing the oxidation–reduction potential of the media and activating the metabolism pathways involving energy and nucleic acid metabolism, protein synthesis, and environmental adaptation, thereby facilitating the nutrient ...
Xi Chen, Yong Zhu, Muhammad Mazhar, Likang Qin   +3 more
wiley   +1 more source

Aberrant Energy Metabolism in Tumors and Potential Therapeutic Targets

Genes, Chromosomes and Cancer, Volume 63, Issue 11, November 2024.
ABSTRACT Energy metabolic reprogramming is frequently observed during tumor progression as tumor cells necessitate adequate energy production for rapid proliferation. Although current medical research shows promising prospects in studying the characteristics of tumor energy metabolism and developing anti‐tumor drugs targeting energy metabolism, there ...
Shuhao Fan, Jianhua Guo, Hui Nie, Huabao Xiong, Yong Xia   +4 more
wiley   +1 more source

Production‐optimized fermentation of antifungal compounds by Bacillus velezensis LZN01 and transcriptome analysis

Microbial Biotechnology, Volume 17, Issue 10, October 2024.
The yields of antimicrobial compounds, such as surfactin, fengycin, shikimic acid, and myriocin, increased or were observed in the optimized fermentation CFS. In conclusion, fermentation conditions improved the antifungal activity of the LZN01 strain and influenced the expression of genes involved in the synthesis of antimicrobial compounds.
Jiale Hu, Zhigang Wang, Weihui Xu
wiley   +1 more source

Biomarcadores na encefalopatia séptica: revisão sistemática dos estudos clínicos Biomarkers in septic encephalopathy: a systematic review of clinical studies

Revista Brasileira de Terapia Intensiva, 2013
OBJETIVO: O objetivo deste estudo foi revisar sistematicamente a importância da enolase específica neuronal e S100B para diagnóstico e monitorização da encefalopatia séptica.
Paula Veriato Zenaide, Dimitri Gusmao-Flores   +1 more
doaj  

From Proteome Mining to Structural Validation: Phosphopyruvate Hydratase as a Structurally Tractable Drug Target in Kinetoplastid Parasites

Abstract Chagas disease, caused by Trypanosoma cruzi , demands novel therapeutic strategies that overcome the toxicity and limited efficacy of current treatments. To address this need, herein we report an integrative, target-centric strategy that combines parasite proteome mining ...
Luis Daniel Goyzueta-Mamani, Haruna Luz Barazorda-Ccahuana, Michelle G. Ng, Laura Pineda, José L. Medina-Franco, Mónica Florin-Christensen, Eduardo Antonio Ferraz Coelho, Carmenza Spadafora, Miguel Angel Chávez-Fumagalli   +8 more
openaire   +1 more source

Enolase AmEno15, a Promising Candidate for Understanding the Infectious Process of <i>Anaplasma marginale</i>. [PDF]

Int J Mol Sci
López-López MDS, Aguilar-Díaz H, Burgos-Solorio A, Quiroz-Castañeda RE.   +3 more
europepmc   +1 more source

Subtractive proteo-genomics and model-based druggability analyses prioritized nitrate reductase-A subunit-α as potential therapeutic target against MDR pneumonia; a homology-based approach. [PDF]

BMC Microbiol
Begum K, Aiman S, Khan A, Mumtaz MN, Ali F, Hussain SA, Khan S, Shaik MR.   +7 more
europepmc   +1 more source

Heterodera schachtii enolase does not elicit canonical immune responses in Arabidopsis thaliana. [PDF]

Sci Rep
Euler MF, Sumaya NPDN, Aslam S, Lerch J, Mendy B, Grundler FMW.   +5 more
europepmc   +1 more source

Metagenome-informed metaproteomics methodology: a new breakthrough in revealing the mechanisms of host-microbiota-diet interactions in inflammatory bowel disease. [PDF]

Front Cell Dev Biol
Zhang S, Xu Q.
europepmc   +1 more source

Protein composition and nutritional evaluation of three <i>Polygonatum</i> Mill species: A comparative analysis. [PDF]

Food Chem X
Liu C, Cao Y, Zhao Y, Lu S, Xia Q.
europepmc   +1 more source