Results 181 to 190 of about 21,742 (223)

Phosphorylcholine Coating of Iron Oxide Nanoparticles

Journal of Colloid and Interface Science, 1999
In order to develop thin-walled superparamagnetic nanoparticle suspensions as a contrast agent for magnetic resonance imaging, phosphorylcholine PC was used to coat iron oxide cores of 5 nm. Weak stable positively charged suspensions can be obtained at concentration greater than 3 mmol.l-1 (corresponding to about 3.2 molecules per nm2), while the ...
François Hindré
exaly   +3 more sources

Somatic Mutation in Anti‐Phosphorylcholine Antibodies

Immunological Reviews, 1987
A detailed analysis of the genes and proteins that participate in the murine immune response to PC has provided key insights at the structural level into the phenomenon of somatic mutation in B cells. Most anti-PC antibodies are encoded by 1 VH gene of the S107 subfamily, and 3 VK genes, VKT15 of the VK22 subfamily, VKM3 from the VK8 subfamily, and ...
U V, Malipiero, N S, Levy, P J, Gearhart
openaire   +2 more sources

Immune Response to Phosphorylcholine

The Journal of Immunology, 1977
Abstract Anti-idiotypic antibody raised against the BALB/c myeloma proteins TEPC-15 or HOPC-8 inhibits induction of the immune response to phosphorylcholine (PC). (Fab′)2 and Fab′ fragments from anti-idiotype serum were prepared and anti-idiotypic antibody was purified by absorption and elution from idiotype or anti-IgG subclass ...
Heinz Köhler, Bruce C Richardson, Donald A Rowley, Sue Smyk   +3 more
openaire   +1 more source

Unsaturated Analogues of Phosphorylcholines

Phosphorus, Sulfur, and Silicon and the Related Elements, 1999
Abstract The vinyl esters of phosphorus acids, containing onium group in β-position, for example, betaines type A and B (X = N, P), have a number of features, attracting to them significant attention of researchers.[1] First of all, these compounds are interesting as examples of hydrolytically stable inhibitors of acetylcholinesteraze, posessing ...
Serge E. Pipko, Yuri V. Balitsky, Anatoli D. Sinitsa   +2 more
openaire   +1 more source

Tuftsin-phosphorylcholine attenuate experimental autoimmune encephalomyelitis

Journal of Neuroimmunology, 2019
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) which carries a significant burden of morbidity and mortality. Herein we examine the effects of acute treatment with tuftsin-phosphorylcholine (TPC), a novel immune-modulating helminth derived compound, on a murine model of MS.
Natalia S, Novikova, Anastasia S, Diatlova, Kristina Z, Derevtsova, Elena A, Korneva, Tamara V, Viktorovna, Yuri, Ostrinki, Lital, Abraham, Shir, Quinn, Yahel, Segal, Leonid P, Churilov, Miri, Blank, Yehuda, Shoenfeld, Rina, Aharoni, Howard, Amital   +13 more
openaire   +2 more sources

Neutrophil adhesion on phosphorylcholine-containing polyurethanes

Biomaterials, 1998
Polyurethanes have been synthesized using glycerophosphorylcholine (GPC) as a chain extender. By altering the ratio of GPC to butanediol (BD), a series of polymers was obtained composed of different contents of phosphorylcholine. Bulk and surface characterization of the polymers was carried out.
L Y, Yung, S L, Cooper
exaly   +3 more sources

Phosphorylcholine antigens from Nippostrongylus brasiliensis. I.--Anti-phosphorylcholine antibodies in infected rats and location of phosphorylcholine antigens.

Annales d'immunologie, 1980
The anti-phosphorylcholine (PC) antibody synthesis was investigated in the rat after infection with the nematode Nippostrongylus brasiliensis. Serum IgM and IgG antibodies were demonstrated from day 2 or 3 post-infection. Intestinal IgA-antibody synthesis began shortly after the worms reached the intestine.
P, Péry, G, Luffau, J, Charley, A, Petit, P, Rouze, S, Bernard   +5 more
openaire   +1 more source

Choline Administration Elevates Brain Phosphorylcholine Concentrations

Journal of Neurochemistry, 1982
Abstract: The phosphorylcholine concentration of rat brain rises and falls in response to parallel changes in the concentration of circulating choline. A single oral dose of choline chloride (20 mmol/kg) elevated whole‐brain concentrations of both choline and phosphorylcholine 5 h after administration; a greater proportion of exogenously administered ...
W R, Millington, R J, Wurtman
openaire   +2 more sources

Dipetalonema viteae: Phosphorylcholine and non-phosphorylcholine antigenic determinants in infective larvae and adult worms

Experimental Parasitology, 1986
The humoral immune response of Balb/c mice to live infective larvae or adult worm extract of Dipetalonema viteae is composed of two antibody populations either with or without specificity for phosphorylcholine. Absorption of immune serum on phosphorylcholine-Sepharose and separation of the antibody population demonstrated that anti-larvae serum ...
M, Gualzata, N, Weiss, C H, Heusser
openaire   +2 more sources

IgM Waldenstroem with specificity against phosphorylcholine

Biochemistry, 1975
Anti-phosphorylcholine specificity has recently been shown to occur with relatively high incidence among IgA myeloma proteins secreted by oil-induced plasma cell tumors in the BALB/c strain of mice. A similar screening of human myeloma sera indicates that in man activity for phosphorylcholine is very rare.
W, Riesen, S, Rudikoff, R, Oriol, M, Potter   +3 more
openaire   +2 more sources