A study of clinical strains of Pseudomonas Aeruginosa and the investigation of antibiotic resistance mechanisms in the multidrug resistant strain PA13 [PDF]
, 2008 Thirteen clinical strains of bacteria from two Irish hospitals were identified as Pseudomonas aeruginosa using classical methods, API 20NE and Biolog GN. Their identification was confirmed by 16S rRNA gene sequencing.
Ferguson, Damien
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Insights into the biochemical strategies of adaptation to heat stress in the hyperthermophilic archaeon Pyrococcus furiosus [PDF]
, 2015 Organisms that thrive optimally at temperatures above 80°C are called hyperthermophiles. These prokaryotes have been isolated from a variety of hot environments, such as marine geothermal areas, hence they are usually slightly halophilic.
Esteves, Ana Maria
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Analysis of bio synthetical pathways of Nootkatone generated via retrosynthetic biochemical algorithms [PDF]
, 2021 Joaquim Diogo Luzirão de Almeida
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DESIGN AND EVALUATION OF HMP KINASE ANALOGS AS THIAMINE PATHWAY INHIBITORS [PDF]
, 2016 Current bacterial chemotherapy faces an overwhelming reduction in efficacy due to an increase in bacterial resistance; resulting in a higher clinical demand for novel therapeutics and the investigation for their respective targets.
Lopez, Diego A.
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Addressing The Threat Of Multidrug Resistant Infectious Diseases By Synthesis Of Novel Aminoglycoside Antibiotics [PDF]
, 2018 The ever-growing increase in multidrug resistant infectious diseases is one of the major cause of human mortality, and there is an inherent need for the development of new antibiotics.
Sati, Girish Chandra
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Part – I: Development of a Two-step Regiospecific Synthetic Route for Multigram Scale Synthesis of Β-carboline Analogs for Studies in Primates as Anti-alcohol Agents,part – II: Design and Synthesis of Novel Antimicrobials for the Treatment of Drug Resistant Bacterial Infections Part – Iii: A Novel Synthetic Method for the Synthesis of the Key Quinine Metabolite (3S)-3-Hydroxyquinine [PDF]
, 2017 PART – I Development of a Two-Step Regiospecifc Synthetic Route for Multigram-Scale Synthesis of β-Carboline Analogs for Studies in Primates as Anti-Alcohol Agents β-Carboline and their derivatives are important structural motifs in synthetic organic and
Tiruveedhula, Veera Venkata Naga Phani Babu
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Branched aminoglycosides: biochemical studies and antibacterial activity of neomycin B derivatives [PDF]
, 2005 -The C5 00 -OH group in neomycin B was glycosylated with a variety of mono-and di-saccharides to probe the effect of introduction of additional binding elements on antibacterial activity and interaction with the aminoglycosides modifying enzyme APH(3 0 )-
Dalia Shallom-Shezifi +7 more
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Structural basis of ligand binding to 3',5'' -aminoglycoside O-phosphotransferase type IIIa [PDF]
3',5"-aminoglycoside O-phosphotransferase type IIIa (APH(3')-IIIa) is an enzyme produced by pathogenic Gram-positive bacteria such as Enterococci and Staphylococci.
Fong, Desiree Ho-Chi.
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