Successful seizure control with cenobamate in juvenile myoclonic epilepsy. [PDF]
Epileptic Disorders, Volume 27, Issue 2, Page 307-310, April 2025.
Tényi D, Horváth R, Janszky J.
europepmc +2 more sources
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski+3 more
wiley +1 more source
Elevated photic response is followed by a rapid decay and depressed state in ictogenic networks [PDF]
Objective: The switch between nonseizure and seizure states involves profound alterations in network excitability and synchrony. In this study, we aimed to identify and compare features of neural excitability and dynamics across multiple zebrafish ...
D'gama, Percival P+10 more
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Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]
Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana+5 more
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Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Charles W. Diamond+3 more
wiley +1 more source
Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health [PDF]
Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation.
Diego A. Golombek+6 more
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Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]
The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji+21 more
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Effects of photoperiod extension on clock gene and neuropeptide RNA expression in the SCN of the Soay sheep [PDF]
In mammals, changing daylength (photoperiod) is the main synchronizer of seasonal functions. The photoperiodic information is transmitted through the retino-hypothalamic tract to the suprachiasmatic nuclei (SCN), site of the master circadian clock.
Dardente, Hugues+4 more
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High-frequency neural oscillations and visual processing deficits in schizophrenia [PDF]
Visual information is fundamental to how we understand our environment, make predictions, and interact with others. Recent research has underscored the importance of visuo-perceptual dysfunctions for cognitive deficits and pathophysiological processes in
Lana, L., Tan, H.-R.M., Uhlhaas, P.J.
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Aspects of average response computation by aperiodic stimulation [PDF]
A mathematical analysis of the variance of the average evoked-response computation as a function of the numberN of stimuli presented is made for the case when the response is disturbed by additive stationary noise.
Hoopen, M. ten, Reuver, H.A.
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