Results 51 to 60 of about 31,168 (186)

Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy

Journal of Sleep Research, EarlyView.
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash, Ishani Shah, Guohao Ni, Sridhar Vasudevan, Aarti Jagannath, Russell G. Foster   +5 more
wiley   +1 more source

Magnetic resonance spectroscopy in migraine: what have we learned so far? [PDF]

, 2012
Objective: To summarize and evaluate proton (H-1) and phosphorus (P-31) magnetic resonance spectroscopy (MRS) findings in migraine. Methods: A thorough review of H-1 and/or P-31-MRS studies in any form of migraine published up to September 2011 ...
Achten, Eric, Paemeleire, Koen, Reyngoudt, Harmen   +2 more
core   +2 more sources

Long‐term sub‐erythemal UVB exposure does not impact circadian rhythms in mice under standard and rotating shift light conditions

Photochemistry and Photobiology, EarlyView.
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer, Sean J. Cone, Rachel Bernstein, Elizabeth Schuetz, Narayani Prasad Kar, Bala S. C. Koritala, Shobhan Gaddameedhi   +6 more
wiley   +1 more source

Ictus Emeticus Induced by Photic Stimulation

Pediatric Neurology Briefs, 1994
Occipitotemporal seizures induced by intermittent photic stimulation in three children with brain injuries, aged 10 to 13 years, are reported from the Institute of Developmental Neuropsychiatry, University of Pisa, Italy.
openaire   +4 more sources

The neurochemical basis of photic entrainment of the circadian pacemaker [PDF]

Circadian rhythmicity in mammals is controlled by the action of a light-entrainable hypothalamus, in association with two cell clusters known as the supra chiasmatic nuclei (SCN).
Buckley, Becky, Lutton, Lewis M., Rea, Michael A.   +2 more
core   +1 more source

Preliminary trial of photic stimulation for premenstrual syndrome

Journal of Obstetrics and Gynaecology, 1997
In an open study 17 women with confirmed, severe and long-standing premenstrual syndrome used photic stimulation with a flickering red light, every day for up to four menstrual cycles. At the end of treatment prospectively recorded median luteal symptom scores were reduced by 76% (95% confidence interval 54-93, P < 0.001), with clinically and ...
D. J. Anderson, Deborah A. Ridout, N. J. Legg   +2 more
openaire   +2 more sources

Effects of heme oxygenase isozymes on Leydig cells steroidogenesis [PDF]

, 2009
In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known HO inducer, hemin, increased
Besio Moreno, Marcos Alberto, Cymeryng, Cora Betriz, Monzón, Casandra Margarita, Pagotto, Romina María del Luján, Pignataro, Omar Pedro, Piotrkowski, Barbara, Reche, Cecilia   +6 more
core   +1 more source

MTSS2 ‐Related Disorder: Refining the Phenotype in Four New Cases and Literature Review

American Journal of Medical Genetics Part A, Volume 197, Issue 6, June 2025.
ABSTRACT MTSS2 encodes a protein highly expressed in the central nervous system, with a crucial role in neurodevelopment. The de novo recurrent variant c.2011C>T (p.Arg671Trp) was first identified in 2022 as cause of Intellectual Developmental Disorder with ocular anomalies and distinctive facial features (OMIM#620086).
Angela De Dominicis, Francesca Piceci Sparascio, Fabrizia Stregapede, Alessandra Terracciano, Daniela Verrigni, Francesca Romana Lepri, Sarah Cetola, Maria Lisa Dentici, Federico Vigevano, Antonio Novelli, Nicola Specchio, Marina Trivisano, Maria Cristina Digilio   +12 more
wiley   +1 more source

The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]

, 2015
The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M., Herman, James P., Holland, Jenna, Morano, Rachel, Ottaway, Nickki, Perez-Tilve, Diego, Pressler, Joshua W., Sandoval, Darleen A., Seeley, Randy J., Sorrell, Joyce, Woods, Stephen C.   +10 more
core   +2 more sources

Enhanced detection of glutamate via transverse relaxation encoding with narrowband decoupling in the human brain

Magnetic Resonance in Medicine, Volume 93, Issue 6, Page 2278-2286, June 2025.
Abstract Purpose This study aims to improve the detection of glutamate (Glu) concentration and T2 using an enhanced transverse relaxation encoding with narrowband decoupling (TREND) technique. Methods A new editing pulse was designed to simultaneously invert both Glu H3 spins (2.12 ppm and 2.05 ppm) while minimizing the excitation of Glu H4 ...
Li An, Sungtak Hong, Tara Turon, Adriana Pavletic, Christopher S. Johnson, John A. Derbyshire, Jun Shen   +6 more
wiley   +1 more source