Results 81 to 90 of about 32,760 (219)

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E., Dai, Jennifer B., Daigle, Renee, Forman, Stuart A., Halpin, Elizabeth S., Jounaidi, Youssef, Marte-Oquendo, Francisco, Porco, John A., Schaus, Scott E., Trilles, Richard, Xu, Wenqing, Yang, Xiaoxuan, Yu, Buwei   +12 more
core   +1 more source

Semiology in spontaneous versus cortical stimulation‐induced seizures during SEEG: A within‐patient comparison study

Epilepsia Open, Volume 11, Issue 2, Page 488-503, April 2026.
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan, Stéphane Dufau, John Phamnguyen, Arash Kahrom, Donald Craig, Aileen McGonigal   +5 more
wiley   +1 more source

Juvenile idiopathic epilepsy in Egyptian Arabian foals, a potential animal model of self‐limited epilepsy in children

Journal of Veterinary Internal Medicine
Background Juvenile idiopathic epilepsy (JIE) is categorized as a generalized epilepsy. Epilepsy classification entails electrocortical characterization and localization of epileptic discharges (ED) using electroencephalography (EEG).
Monica Aleman, Ruba Benini, Sami Elestwani, Tatiana Vinardell   +3 more
doaj   +1 more source

Light and tidal inundation and exposure regulate the sensitivity of estuarine benthic greenhouse gas fluxes to warming and ocean acidification

Limnology and Oceanography, Volume 71, Issue 4, April 2026.
Abstract Coastal sediments are globally significant sources and sinks of greenhouse gases (GHGs), yet their contributions to climate feedbacks of warming and ocean acidification remain uncertain, in part due to limited understanding of short‐term variability.
Michelle N. Simone, Joanne M. Oakes, Kai G. Schulz, Bradley D. Eyre   +3 more
wiley   +1 more source

The neurochemical basis of photic entrainment of the circadian pacemaker [PDF]

Circadian rhythmicity in mammals is controlled by the action of a light-entrainable hypothalamus, in association with two cell clusters known as the supra chiasmatic nuclei (SCN).
Buckley, Becky, Lutton, Lewis M., Rea, Michael A.   +2 more
core   +1 more source

Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice [PDF]

, 2015
Light has direct effects on sleep and wakefulness causing arousal in diurnal animals and sleep in nocturnal animals. In the present study, we assessed the modulation of light-induced sleep by melanopsin and the histaminergic system by exposing mice to ...
Colas, Damien, Heller, H. Craig, Ikeme, Jesse, Muindi, Fanuel, Ruby, Norman F.   +4 more
core   +3 more sources

Seasonal nitrate drawdown transitions lake ecosystems from phosphorus to nitrogen deficiency in annual cycles

Limnology and Oceanography, Volume 71, Issue 4, April 2026.
Abstract Phytoplankton biomass is often limited by nitrogen (N) and/or phosphorus (P). Quantifying the relative availability of N and P in an ecosystem is useful in indicating nutrient limitation status. In subtropical lakes, nitrate availability generally follows a seasonal pattern with maxima in the late winter/early spring and minima in late summer ...
Jasmine K. Stovall, Nicole D. Wagner, Katelyn McKindles, Michelle Neudeck, Matthew Rich, George S. Bullerjahn, J. Thad Scott   +6 more
wiley   +1 more source

Importance of the attention of children in early childhood

Acta Médica del Centro, 2008
A descriptive and cross-sectional study with a universe formed by 26 children between the ages of 0 and five who attended the Early Childhood Attention Services of the Arnaldo Milián Castro Provincial University Hospital during the period from January ...
Silvia L. Álvarez Romero, Arelys Fleitas Hernández, Esledy Carvajal González   +2 more
doaj  

EEG Patterns Orienting to Lafora Disease Diagnosis—A Case Report in Two Beagles

Frontiers in Veterinary Science, 2020
Lafora Disease (LD) is a rare, fatal, late-onset, progressive form of myoclonic epilepsy, occurring in humans and dogs. Clinical manifestations of LD usually include seizures, spontaneous and reflex myoclonus with contractions of the neck and limb ...
Helga Demeny, Bogdan Florea, Flaviu Tabaran, Cecilia Gabriella Danciu, Laurent Ognean   +4 more
doaj   +1 more source

Heatwaves and Anthropogenic Light May Disrupt Phototaxis‐Based Behaviours That Regulate Early‐Life Migrations of Fish

Freshwater Biology, Volume 71, Issue 4, April 2026.
ABSTRACT Though many fish larvae exhibit phototaxis, its adaptive value is underexplored. Larval fish rely on cues to guide them to suitable nursery habitats and phototaxis enables larvae to react to environmental cues. In the Anthropocene, innate phototactic behaviour might also be disrupted via climate change and habitat alteration.
Barnaby John Roberts, Jan Baer, Albert Ros, Alexander Brinker   +3 more
wiley   +1 more source