Results 211 to 220 of about 5,920,647 (307)

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

UV Response of the Green Fluorescent Protein Chromophore: Insights from Ab Initio Nonadiabatic Simulations. [PDF]

J Phys Chem Lett
Thongyod W, Lu T, Bai Y, Punwong C, Glover WJ.   +4 more
europepmc   +1 more source

Controllable Carbon Shell Encapsulation via Rapid Joule Heating Calcination for High‐Performance Asymmetric Supercapacitor With Suppressed Self‐Discharge and Robust Cycling Stability

Advanced Science, EarlyView.
The H‐Fe3O4@C negative electrode and H‐NiCo2S4@C positive electrode are designed through a controllable carbon shell encapsulation strategy. The as‐constructed asymmetric supercapacitor presents robust cycling stability with 93.7% capacity retention after 25 000 cycles.
Qiang Zhou, Zheng Yang, Zhen Cao, Xulan Zheng, Xiao Yan, Yunsong Li, Xinsheng Zhao, Yuxiao Lin, Xiaoxiao Li   +8 more
wiley   +1 more source

Patient Perspectives on the Use of Artificial Intelligence in Malignant Melanoma Diagnosis. [PDF]

Dermatol Pract Concept
Lykke Lorentzen K, Mikkelsen KL, Boe LS, Rasmussen GS, Spaich EG, Thomsen KG.   +5 more
europepmc   +1 more source

Use of the “Ru‐1O2‐Hydrazide” System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells

Advanced Science, EarlyView.
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun, Kaihong Wang, Haifu Sun, Kemei Tao, Xiang Li, Xiuhua Zhao, Shuang Qiu   +6 more
wiley   +1 more source

In Situ Imaging Reveals Efficient Charge Separation in Monolayer MoS₂-WS₂ Type-II Heterojunctions. [PDF]

J Am Chem Soc
Huang Q, Wang Z, Liu R, Yao H, Ni C, Bo T, Wu S, Sun F, Fan F, Mirkin MV.   +9 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

The Mascarene Archipelago, a Data-Poor Region for Mobulid Rays: First Records, Seasonal Patterns and Conservation Implications. [PDF]

Ecol Evol
Harris JL, Crochelet E, Mohesh P, Stevens GMW.   +3 more
europepmc   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

Advanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka, Zhaolin Liu, Ivan P. Parkin, Guanjie He   +3 more
wiley   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source