Results 121 to 130 of about 4,279 (175)

Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin   +6 more
wiley   +1 more source

Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease‐linked spectra‐pathological signatures

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Confocal Raman microspectroscopy for spatially resolved tissue analysis: technology setup, spectra‐pathological signatures derived from computational methods, and tissue‐level insights for biomedical research and clinical applications. Abstract Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of ...
Nektarios A. Valous   +2 more
wiley   +1 more source

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

open access: yesSmall, Volume 21, Issue 39, October 2, 2025.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico   +2 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, Volume 6, Issue 10, October 2025.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

Synthesis of Anthraquinone Mono‐ and Diboron Complexes with Near‐Infrared Panchromatic Absorption

open access: yesChemistry – A European Journal, Volume 31, Issue 53, September 19, 2025.
Anthraquinone boron complexes bearing β‐iminoenolate ligand(s) exhibit strongly substituent‐dependent absorption properties. Unsubstituted monoboron and diboron complexes show sharp UV–Vis–NIR absorption spectra resulting from increased molecular rigidity induced by boron coordination.
Yasuhiro Kubota   +4 more
wiley   +1 more source

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