Results 141 to 150 of about 4,077 (269)

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

A Reproducible MRI‐Based Pipeline for Longitudinal Tracking of Laser‐Assisted Bioprinted Cells in Three‐Dimensional Constructs

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Laser‐assisted bioprinting was used to deposit iron oxide‐labelled endothelial cells in predefined patterns onto SCAP‐seeded gelatin biopapers to assemble multilayer constructs of increasing thickness. T2*‐weighted MRI monitored constructs for up to 35 days.
Mina Medojević, Charles Handschin, Ayako Washio, Malou Lea, Laurence Dallet, Aleksandar Jakovljević, Emeline J. Ribot, Olivia Kérourédan   +7 more
wiley   +1 more source

Transgenic Mixed‐Linkage‐Glucan Enhancement Affects Root Characteristics and Decomposition in Soils of Contrasting Vegetation History

GCB Bioenergy, Volume 18, Issue 10, October 2026.
Incubations with fine and coarse roots of transgenic and wild type bioenergy sorghum showed that transgenic roots had higher content of mixed‐linkage glucan and resulted in greater soil microbial biomass than the roots of the vector control plants.
Majid Mahmoodabadi, Sang‐Jin Kim, Poulamee Chakraborty, Andrey Guber, Alexandra Kravchenko, Federica Brandizzi   +5 more
wiley   +1 more source

Optical Basicity of Glasses: Review and Application in Nuclear Glass Formulation

International Journal of Applied Glass Science, Volume 17, Issue 4, October 2026.
A self‐consistent set of optical basicity (OB) values was compiled and evaluated for 95 binary oxides using electronegativity, ionic–covalent, and optical‐property approaches, providing a robust basis for estimating the basicity of complex compounds and glasses.
John McCloy, John Bussey, Wyatt Kiff
wiley   +1 more source

Non‐Monotonic Changes in the Thermal Conductivity of Conjugated Polymer Films with Increasing Levels of Chemical Doping

Advanced Functional Materials, Volume 36, Issue 72, 7 September 2026.
Thermal conductivity changes non‐monotonically as regioregular (RR) and regiorandom (RRa) P3HT films are doped with F4TCNQ as a function of the extent to which P3HT is doped: an increase in thermal conductivity is observed upon lightly doping P3HT compared to the undoped film, followed by a decrease in the heavily doped regime. ABSTRACT The performance
Reid W. Wilson, Xinping Shi, Diego Garcia Vidales, Abigail Slimp, Zerina Mehmedović, Alexander F. Simafranca, Eric C. Wu, Sarah H. Tolbert, Richard B. Wilson, Benjamin J. Schwartz   +9 more
wiley   +1 more source

Optically Active Birefringent Polymer–Lipid Hybrid Microparticles With Dual‐Stimuli Responsiveness

Advanced Optical Materials, Volume 14, Issue 33, 4 September 2026.
The present study reports on geometrically tunable, magnetic and NIR‐stimuli‐responsive anisotropic microparticles that exhibit intrinsic birefringence due to their lamellar crystalline architecture, enabling label‐free detection under a polarized light.
Burcu Okmen Altas, Emre Bukusoglu, Nihal Aydogan   +2 more
wiley   +1 more source

Dual‐Acceptor Engineered Multimodal Phototheranostic NIR‐II AIEgens for Orthotopic Breast Cancer Treatment

Aggregate, Volume 7, Issue 9, September 2026.
A robust NIR‐II AIE small molecule with multimodal phototheranostic features was rationally constructed through a dual‐acceptor engineering strategy, which enables exceptional NIR‐II fluorescence–photoacoustic–photothermal trimodal imaging and synergistic photodynamic–photothermal therapy in a mouse orthotopic breast cancer model under 808 nm laser ...
Miaomiao Kang, Yu Pei, Zengming Yang, Yinzhen Pan, Zhijun Zhang, Xue Li, Dong Wang, Ben Zhong Tang   +7 more
wiley   +1 more source