Results 261 to 270 of about 25,792 (294)

Stable near‐infrared‐IIb dyes based on bis‐Pd(II) complexes of bis(TIPS‐ethynyl)‐substituted doubly N‐confused hexaphyrins

open access: yesJournal of the Chinese Chemical Society, Volume 72, Issue 10, Page 1090-1100, October 2025.
A novel anisotropically π‐extended hexaphyrin dye, t‐Pd2‐3, exhibits abnormally low‐energy absorption and emission beyond 1500 nm within the NIR‐IIb biological window. The specific optical feature of t‐Pd2‐3 contributed to its being utilized as a NIR‐IIb‐excitation‐induced photoacoustic contrast agent for deeper tissue imaging applications. Abstract We
Yuriha Nishiguchi   +7 more
wiley   +1 more source

Repurposing the Antidepressant Sertraline: A Systematic Scoping Review of Its Anticancer Mechanisms

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
A multi‐targeted antidepressant with strong preclinical anticancer activity, sertraline represents a candidate for therapeutic repurposing. ABSTRACT Drug repurposing offers a cost‐effective and time‐efficient strategy for identifying new cancer therapies. Sertraline, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has shown promising
Ciara B. Blum   +4 more
wiley   +1 more source

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

open access: yesSmall, Volume 21, Issue 39, October 2, 2025.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico   +2 more
wiley   +1 more source

Photoacoustic imaging detects cerebrovascular pathological changes in sepsis. [PDF]

open access: yesPhotoacoustics
Wang Z   +6 more
europepmc   +1 more source

Illuminating the Unseen: Dynamic Butyrylcholinesterase Detection Driving Precision Medicine and Environmental Toxicology

open access: yesSmartMat, Volume 6, Issue 5, October 2025.
Butyrylcholinesterase (BChE), a key member of the cholinesterase family, plays an indispensable role in neural signal regulation, Alzheimer's disease therapeutic development, metabolic homeostasis, and clinical toxicology diagnostics. This study provides a comprehensive review of existing analytical methodologies for BChE detection, along with their ...
Min Liu   +7 more
wiley   +1 more source

Normal and melanoma skin visualized, quantified and compared by in vivo photoacoustic imaging. [PDF]

open access: yesPhotoacoustics
von Knorring T   +7 more
europepmc   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, Volume 6, Issue 10, October 2025.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

Special issue introduction: Ultrafast photoacoustics

open access: yesPhotoacoustics
Vitalyi E. Gusev   +2 more
doaj   +1 more source

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