Results 21 to 30 of about 4,613 (127)

Efficacy of energy‐based devices on episiotomy pain and healing: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Episiotomy is a common obstetric procedure often associated with significant postpartum pain and delayed wound healing. Conventional treatments provide limited relief and might not be suitable for all women. Energy‐based therapies, including infrared irradiation and low‐level laser therapy (LLLT), a non‐thermal photo biomodulation ...
Shira Regev‐Sadeh, Chen Nahshon, Nadav Cohen, Ofer Lavie, Ariel Zilberlicht   +4 more
wiley   +1 more source

A randomized controlled trial of home‐applied dual‐light photodynamic therapy during supportive periodontal care (HOPE‐CP study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a common, chronic inflammatory disease that relies heavily on effective daily oral hygiene for long‐term control. Light‐based therapies have demonstrated strong antibacterial potential; however, their effectiveness in regular home use remains unexplored.
Saila Pakarinen, Hannamari Välimaa, Anna M. Heikkinen, Marja Noponen, Heikki Alapulli, Riitta K. T. Saarela, Taina Tervahartiala, Ismo T. Räisänen, Timo Sorsa, Dimitra Sakellari, Tommi Pätilä   +10 more
wiley   +1 more source

Analgesic Efficacy of Low‐Level Laser Therapy for Postoperative Endodontic Pain: A Systematic Review and Meta‐Analysis

Australian Endodontic Journal, EarlyView.
ABSTRACT This systematic review analysed the analgesic efficacy of low‐level laser therapy (LLLT) compared to conventional drug therapy and placebo for postoperative pain in endodontics. PubMed, PubMed Central, Scopus, LILACS, SciELO, Virtual Health Library, Embase and Open Gray were searched.
Gabriela Bonacina, Rafael Chies Hartmann, Maximiliano Schünke Gomes, Daiana Elisabeth Böttcher   +3 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Machine Learning Model for Predicting Postoperative Pain in Cases of Irreversible Pulpitis

International Endodontic Journal, EarlyView.
ABSTRACT Aim Postoperative pain is a frequent clinical concern following endodontic treatment. This study aimed to develop and validate supervised machine learning models to predict the occurrence of postoperative pain in cases of irreversible pulpitis.
Pedro Felipe de Jesus Freitas, Ingrid Luiza Mendonça Cunha, Thalita de Paris Matos, Flares Baratto‐Filho, Bianca Marques de Mattos de Araujo, Manoel Damião Sousa‐Neto, Leandro de Moura Martins, Fernando José Herkrath, Emílio Carlos Sponchiado‐Júnior, Cristiano Miranda de Araujo   +9 more
wiley   +1 more source

Photobiomodulation and platelet‐rich fibrin in the gastrocnemius muscle submitted to calcaneal tendinopathy in rats

Photochemistry and Photobiology, EarlyView.
The study evaluated different treatments for calcaneal tendinopathy in rats, focusing on the gastrocnemius muscle. Photobiomodulation (PBM), advanced platelet‐rich fibrin (A‐PRF), and their combination were tested. Treated animals showed improved muscle strength between 7 and 21 days, but without significant recovery of muscle fibers.
Pâmela Andressa Pauletto, Caroline Hammerschmitt Eduardo Schmitt, Fransael Franklyn Araújo da Silva, Maria Eduarda Luckner, Lucinéia de Fátima Chasko Ribeiro, Márcia Miranda Torrejais, Gladson Ricardo Flor Bertolini   +6 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

Photochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin, Carolina Sayuri Wajima, Fábio Roberto de Souza Batista, Naara Gabriela Monteiro, Isadora Castaldi Sousa, Valdir Gouveia Garcia, Dóris Hissako Matsushita, Letícia Helena Theodoro, Roberta Okamoto   +8 more
wiley   +1 more source

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

Periodontology 2000, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin, Troy B. Tran, Paras Ahmad, Nima Farshidfar, Georgios E. Romanos, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source