Results 61 to 70 of about 6,348 (145)

Salivary Methotrexate as a Predictor of Oral Mucositis in Hematological Cancer Patients: A Phase II Randomized, Double‐Blind Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate the efficacy of prophylactic photobiomodulation therapy (PBMT) in preventing oral mucositis (OM) and to assess serum and salivary methotrexate (MTX) levels as predictors of OM in adults receiving high‐dose methotrexate (HD‐MTX).
Letícia Rodrigues‐Oliveira, Carolina Guimarães Bonfim, Ana Leticia Mores, Natalia Rangel Palmier, Henrique Ballassini Abdalla, Juliana Trindade Clemente‐Napimoga, Iara Gonçalves Aquino, Maria Cecilia Querido de Oliveira, Maria Cláudia Cuzzullin, Aljomar Jose Vechiato Filho, Cesar Rivera, Tatiana Natasha Toporcov, Juliana Pereira, Luiz Alcino Gueiros, Rossana Veronica Mendoza López, Manoela Domingues Martins, Marcelo Lazzaron Lamers, Karina Morais‐Faria, Pablo Agustin Vargas, Alan Roger Santos‐Silva, Thais Bianca Brandão, Ana Carolina Prado‐Ribeiro   +21 more
wiley   +1 more source

Effects of photobiomodulation therapy on pulmonary inflammation in chronic asthma: Dosimetric study in an experimental model

Photochemistry and Photobiology, EarlyView.
Photobiomodulation therapy (PBMT) was evaluated across a radiant energy range (1–7.5 J) in a murine model of chronic ovalbumin‐induced asthma to identify the optimal therapeutic dose. PBMT attenuated airway inflammation and remodelling, suppressed Th2 cytokines, and enhanced regulatory immune responses, highlighting a dose‐dependent immunomodulatory ...
Tawany Gonçalves Santos, Cintia Estefano Alves, Aurileia Aparecida de Brito, Bibiana Padilha de Menezes da Silva, Cinthya Cosme Gutierrez Duran, Stella Zamuner, Rodrigo Labat, José Antonio Silva Junior, Maria Cristina Chavantes, Flavio Aimbire, Renata Kelly da Palma, Ana Paula Ligeiro de Oliveira   +11 more
wiley   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

Effect of photobiomodulation on the severity of oral mucositis and molecular changes in head and neck cancer patients undergoing radiotherapy: a study protocol for a cost-effectiveness randomized clinical trial

Trials, 2019
Background Oral mucositis (OM) is the most frequent and debilitating acute side effect associated with head and neck cancer (HNC) treatment.
Allisson Filipe Lopes Martins, Túlio Eduardo Nogueira, Marília Oliveira Morais, Angélica Ferreira Oton-Leite, Marize Campos Valadares, Aline Carvalho Batista, Nilceana Maya Aires Freitas, Cláudio Rodrigues Leles, Elismauro Francisco Mendonça   +8 more
doaj   +1 more source

Oral health‐related quality of life (OHRQoL) in people with dentin hypersensitivity: A systematic review of interventional studies

Periodontology 2000, EarlyView.
Abstract Objective This systematic review, the first in this field, aimed to evaluate if interventions for dentin hypersensitivity (DH) affect patient‐reported oral health‐related quality of life (OHRQoL). Methods A systematic search was conducted across seven electronic databases and gray literature sources, focusing on interventional studies ...
G. Kitsaras, K. Bekes, S. Kumbargere, C. L. Randall, K. Asimakopoulou   +4 more
wiley   +1 more source

Photobiomodulation and Physical Exercise, Impacts on Wrist Muscle Strength and Endurance: A Blinded Randomized Trial

Research in Sports Science
To investigate the effects of photobiomodulation (PBM) at two wavelengths, 850 nm and 660 nm, on the maximum strength and local muscular endurance of the flexor and extensor muscles of the wrist and forearm. This was a ran-domized, single-blind clinical
Pedro Mello Coutinho Fonseca, Larissa Goés de Oliveira, Márcia Rosângela Buzanello, Alberito Rodrigo de Carvalho, Gladson Ricardo Flor Bertolini   +4 more
doaj   +1 more source

Effectiveness of nonsurgical therapy of peri‐implant mucositis: A systematic review

Periodontology 2000, EarlyView.
Abstract Objectives This systematic review intends to respond to the question: “How do clinical parameters change in implants affected by peri‐implant mucositis following different non‐surgical treatment approaches or no treatment in patients monitored for a minimum of six months?” Materials and Methods A search for randomized clinical trials (RCTs) or
Giulia Brunello, Alessandro Antonelli, Ulrike Schulze‐Späte, Francisco Correia, Kathrin Becker   +4 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Heterologous Fibrin Biopolymer as a Key Scaffold for Bone Regeneration: Synergistic Effects with Photobiomodulation and Membrane Therapy

Gels
Bone regeneration remains a clinical challenge, particularly in critical-size defects, motivating the investigation of biomaterials and adjuvant therapies that may support tissue repair.
Matheus Bento Medeiros Moscatel, Bruna Trazzi Pagani, Beatriz Flávia de Moraes Trazzi, Tawana Pascon, Benedito Barraviera, Rui Seabra Ferreira Júnior, Daniela Vieira Buchaim, Rachel Gomes Eleutério, Rogerio Leone Buchaim   +8 more
doaj   +1 more source