Results 161 to 170 of about 42,147 (261)

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide Replication

open access: yesAngewandte Chemie, EarlyView.
A structurally flexible protein catalyzes replication within a dissipative reaction network driven by UVA‐induced disulfide rearrangements. The protein accelerates templated autocatalytic cycles with replication emerging as the dominant pathway.
Éva Bartus   +12 more
wiley   +2 more sources

Photochemical Macrolactonization of Hydroxyaldehydes via C-H Bromination. [PDF]

open access: yesPrecis Chem
Kodaki S   +4 more
europepmc   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng   +9 more
wiley   +1 more source

Alkoxysulfonium Salts Unlock Access to New Aryl Sulfonium Salts for Cross‐Coupling

open access: yesAngewandte Chemie, EarlyView.
Hard‐to‐access (hetero)aryl sulfonium salts are prepared using stable methoxysulfonium salts in combination with the magnesiation of (hetero)aryl bromides. The approach allows access to aryl sulfonium salts bearing electron‐deficient (hetero)aryl rings, or electron‐rich aryl motifs in which the sulfonium motif resides at an alternative position on the ...
Rachel E. Brown   +4 more
wiley   +2 more sources

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

open access: yesAngewandte Chemie, EarlyView.
This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire   +3 more
wiley   +2 more sources

Impacts of Intensified Heatwaves on Escalation of Ozone and Reactive Nitrogen in Summer. [PDF]

open access: yesEnviron Sci Technol
Wang N   +11 more
europepmc   +1 more source

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