Results 181 to 190 of about 42,147 (261)

A Real‐Time Antifouling Multivalent Aptamer Platform for Wash‐Free Electrochemical Detection of Low‐Abundance Biomarkers in Human Plasma

open access: yesAngewandte Chemie, EarlyView.
Detection of low‐abundance proteins at the point‐of‐care is key for early detection and real‐time monitoring. The clinical translation of such assays is hindered by biofouling, matrix variability, and signal instability. RT‐MagMAp assay overcomes these challenges and enables precise protein quantification in human plasma using a hierarchical assembly ...
Payel Sen   +8 more
wiley   +1 more source

Wavelength-resolved heterodimer [2 + 2] photocycloadditions for reversible surface grafting. [PDF]

open access: yesChem Sci
Kanchana D   +5 more
europepmc   +1 more source

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp   +29 more
wiley   +1 more source

Dibenzazepine Bridged Network Polymeric Phthalocyanines as Degradable Heterogeneous Photocatalysts

open access: yesAngewandte Chemie International Edition, EarlyView.
Dibenzazepine photodynamic bridge has been introduced to zinc and cobalt networks phthalocyanines (NP‐Pcs) to obtain degradable heterogeneous photocatalysts. For the first time, light irradiation plays a key role in “design, use and degradation” of NP‐Pcs.
Erem Ahmetali   +4 more
wiley   +1 more source

The Nonadiabatic Nature of the Substituent Effects in Azobenzene

open access: yesAngewandte Chemie International Edition, EarlyView.
Unified nonadiabatic switching: thermal Z→E isomerization of para‐substituted azobenzenes proceeds through a single nonadiabatic rotational pathway. The iconic bell‐shaped Hammett plot is a σp artifact, not a reflection of a mechanistic change, exposing the limits of single‐reference density functional theory (DFT) and establishing activation entropy ...
Jacob Jan van der Wal   +4 more
wiley   +1 more source

Hydration-Dehydration Dynamics in the Desiccation-Tolerant Moss <i>Hedwigia ciliata</i>. [PDF]

open access: yesPlants (Basel)
Singh P   +5 more
europepmc   +1 more source

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