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Supramolecular Theranostic Nanomedicine for In Situ Self-Boosting Cancer Photochemotherapy.

Biomacromolecules, 2023
Although traditional nanomedicines have enhanced the therapeutic efficacy and improved the survival quality of cancer patients, random drug release and drug resistance are deep-rooted problems hindering their clinical application.
Dan Wu   +5 more
semanticscholar   +1 more source

The Construction of Polyphotocage Platform for Anticancer Photochemotherapy

Advanced Functional Materials, 2023
Photocages enable the precise activation of molecular function with light in many research fields, such as anticancer treatment, where remote spatiotemporal control over the release of an active drug is needed.
Maomao He   +10 more
semanticscholar   +1 more source

Intelligent Responsive Nanoparticles with Multilevel Triggered Drug Penetration for Tumor Photochemotherapy.

ACS Applied Materials and Interfaces, 2023
Nanomedicines have contradictory size requirements to overcome systemic barriers and penetrate the tumor extracellular matrix (ECM). Larger-sized nanoparticles (50-200 nm) exhibit prolonged blood circulation half-life and improved tumor enrichment, while
Yale Yue   +9 more
semanticscholar   +1 more source

Synergistic Cancer Photochemotherapy via Layered Double Hydroxide-Based Trimodal Nanomedicine at Very Low Therapeutic Doses.

ACS Applied Materials and Interfaces, 2021
The success of cancer therapy is always accompanied by severe side effects due to the high amount of toxic antitumor drugs that off-target normal organs/tissues.
Jianping Liu   +4 more
semanticscholar   +1 more source

Polysaccharide Nanodonuts for Photochemotherapy‐Amplified Immunogenic Cell Death to Potentiate Systemic Antitumor Immunity Against Hepatocellular Carcinoma

Advanced Functional Materials, 2022
Immunotherapy shows great promise in the treatment of hepatocellular carcinoma (HCC), however, the low response rate of HCC patients to immunotherapy caused by inadequately immunogenic and immunosuppressive tumor microenvironment (TME) is a huge ...
Yaping Wang   +6 more
semanticscholar   +1 more source

Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy.

Molecular Pharmaceutics, 2021
Recently, supramolecular coordination complexes (SCCs) based on photosensitizers as bridging ligands have attracted great attention in cancer therapy owing to their synergistic effect between photodynamic therapy (PDT) and chemotherapy.
Shibo Lv   +5 more
semanticscholar   +1 more source

Psoralen photochemotherapy

Journal of the American Academy of Dermatology, 1987
Psoralens and sunlight have been used by the Egyptians and Indians for hundreds of years for the treatment of vitiligo. The combination of oral psoralens and artificial ultraviolet A (PUVA) therapy was approved for the management of severe psoriasis by the Food and Drug Administration in 1982.
A K, Gupta, T F, Anderson
openaire   +2 more sources

Multifunctional hypoxia-involved gene silencing nanoplatform for sensitizing photochemotherapy.

ACS Applied Materials and Interfaces, 2020
The integration of combinational photochemotherapy could achieve a promoted therapeutic performance by eliminating the frustrating side effects of each constitute, yet is still confronted with severe therapeutic resistances that are associated with tumor
Huimin Wang   +7 more
semanticscholar   +1 more source

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