Results 161 to 170 of about 79,111 (306)

A Nanotherapeutic Agent for Synergistic Tumor Therapy: Co‐Activation of Photochemical‐Biological Effects

Angewandte Chemie, EarlyView.
An organic‐inorganic composite nanotherapeutic agent (HAP@BMPns) was developed for synergistic tumor therapy. HAP@BMPns is triggered by the acidic tumor environment to release the photosensitizer BMP and Ca2+, thereby synergistically activating photochemical‐biological effects through the production of O2−⋅ based Type‐I photochemical reactions and ...
Junwei Liu, Yang Liu, Songsong Zhi, Yonggang Yang, Heejeong Kim, Dapeng Wu, Ge Wang, Tony D. James, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

Effect of photodynamic therapy on cultured tumor cells, comparing photofrin II with hematoporphyrin pentamer

, 1988
Hiroaki Nokura, Y. Miwa, Noboru Sakai, Hiromu Yamada   +3 more
openalex   +2 more sources

Synthesis, Optical and Singlet Oxygen Generation Properties of Phenazinone‐Based Photosensitizer with 5‐Formyl‐2‐Thienyl Substituents

Asian Journal of Organic Chemistry, EarlyView.
Phenazinone chromophore incorporating a carbonyl group into the skeleton is recently found to be a new‐type halogen‐atom‐free‐photosensitizer possessing superior ability in singlet oxygen (1O2) generation. In this work, we have designed and developed the derivative with two 5‐formyl‐2‐thienyl substituents which is expected to lead to improvement of the
Hiroto Tsuyama, Keiichi Imato, Yousuke Ooyama   +2 more
wiley   +1 more source

Exceptionally High Two‐Photon Absorption Cross Sections in Quinoidal Diazaacene‐Bithiophene Derivatives

Angewandte Chemie, EarlyView.
Unlocking new horizons in two‐photon absorption, this study uncovers how specially structured quinoidal‐bithiophene derivatives achieve remarkable two‐photon absorption cross sections in the near‐infrared range. Advanced calculations reveal the interplay of molecular symmetry and strong state coupling, shedding light on the mechanism behind their ...
Gabriel Sauter, Antonia Papapostolou, Audrey Pollien, Sergius Boschmann, Kathleen Fuchs, Pascal Merten, Kerstin Brödner, Frank Rominger, Jan Freudenberg, Uwe H. F. Bunz, Andreas Dreuw, Petra Tegeder   +11 more
wiley   +2 more sources

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith, Saikat Das Sajib, Anne Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez, Erik Knutsen, Kirsten Sandvig, Tore Skotland, Gunhild Mari Mælandsmo, Tore‐Geir Iversen   +10 more
wiley   +1 more source

A Hypoxia‐Triggered Bioreduction of Hydrophilic Type I Photosensitizer for Switchable In Vivo Photoacoustic Imaging and High‐Specificity Cancer Phototherapy

Angewandte Chemie, EarlyView.
A hydrophilic type I phototherapeutic agent (NanoPcN8O) was developed which selectively responded to hypoxic tumor microenvironments and switched on type I photodynamic and photothermal effects as well as a photoacoustic signal for activatable photoacoustic imaging and tumor phototherapy.
Yuan‐Yuan Zhao, Yihui Xu, Xiaojun Zhang, Zixuan Chen, Heejeong Kim, Xingshu Li, Juyoung Yoon   +6 more
wiley   +2 more sources

Fire needle combined with photodynamic therapy for cutaneous infectious granulomatosis caused by mycobacterium chelonae: A case report

Photodiagnosis and Photodynamic Therapy
Mycobacterium chelonae is a non-tuberculous mycobacteria, which can cause skin infectious granuloma through cosmetic injection. This disease's treatment requires a combination of sensitive antibiotics and a lengthy treatment cycle.
Lei Tang, Fujun Huang, Xun Zhou, Mingdan Zhao, Mengya Huang   +4 more
doaj  

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Photodynamic therapy in non-surgical treatment of periodontitis. [PDF]

Sci Rep
Maj A, Kusiak A, Garbacz K, Cichońska D, Świetlik D.   +4 more
europepmc   +1 more source

Antibacterial effects of natural compounds on biofilm formation of Streptococcus mutans

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1426-1433, December 2022., 2022
Abstract Streptococcus mutans is the main cariogenic pathogen in the oral cavity, considered to contribute toward oral diseases. S. mutans is predominantly entrapped in plaque biofilms. Objectives In this study, we surveyed the antibacterial activity of natural compounds in terms of the biofilm production of S. mutans. Material and Methods We extracted
Farideh Kamarehei, Mohsen Mehdiabadi, Fariba Naderi   +2 more
wiley   +1 more source