Results 261 to 270 of about 4,660,211 (356)

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li   +11 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, EarlyView.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

Preclinical Toxicological Characterization of Porphyrin-Doped Conjugated Polymer Nanoparticles for Photodynamic Therapy [PDF]

open access: gold
Matías Daniel Caverzán   +5 more
openalex   +1 more source

Multifunctional Hydrogel‐Based wound Dressings for Scar‐Free Healing: Design Principles, Therapeutic Mechanisms, and Clinical Translation Challenges

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review integrates scar biology with hydrogel‐based therapeutic strategies, offering a phase‐specific framework to correlate hydrogel functions with scar‐influencing events. It highlights innovations such as stimuli‐responsive hydrogels, nanocomposite systems, and 3D‐printed scaffolds, while addressing clinical translation challenges like ...
Haonan Chai   +3 more
wiley   +1 more source

Controlled Dual Activation of Rhenium(I) Photosensitizers and Profluorophores/Prodrugs via a Dissociative Bioorthogonal Tetrazine–Isonitrile Reaction

open access: yesAngewandte Chemie, EarlyView.
Rhenium(I) tetrazylmethyl complexes serve as phosphorogenic bioorthogonal reagents, releasing luminescent and photocytotoxic rhenium(I) 3‐hydroxypyridine complexes and functional payloads upon reaction with 3‐isocyanopropyl derivatives. Their selective lysosomal accumulation in cancer cells and enhanced singlet oxygen photosensitization in acidic ...
Eunice Chiu‐Lam Mak   +2 more
wiley   +2 more sources

Toward Customization of Pickering Emulsion Nanocarriers for Personalized Delivery of Therapeutics in Cancer Treatments: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
Pickering emulsion‐based nanocarriers are emerging as a disruptive innovation in oncology. Their unique structural and functional attributes have now positioned these systems at the forefront of next‐generation smart delivery platforms, capable of improving therapeutic precision, efficacy, and safety.
Nutan Shukla   +6 more
wiley   +1 more source

A Triple Threat Against Ovarian Cancer: Os(II)‐Pt(IV)‐Ceritinib Conjugates for Photodynamic Therapy, Chemotherapy, and Immunogenic Cell Death Induction

open access: yesAngewandte Chemie, EarlyView.
A novel Os(II)‐Pt(IV)‐Ceritinib (Os‐Pt‐Cer) conjugate enables triple‐action anticancer therapy by integrating photodynamic therapy, chemotherapy, and immunogenic cell death (ICD) induction into a single molecule. Upon near‐infrared light activation, this heterobimetallic complex exhibits potent antiproliferative effects in ovarian cancer models ...
Marta Redrado   +10 more
wiley   +2 more sources

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