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Antitumor Effect of Photodynamic Therapy/Sonodynamic Therapy/Sono-Photodynamic Therapy of Chlorin e6 and Other Applications.

Molecular Pharmaceutics, 2023
Chlorin e6 (Ce6) has been extensively researched and developed as an antitumor therapy. Ce6 is a highly effective photosensitizer and sonosensitizer with promising future applications in photodynamic therapy, dynamic acoustic therapy, and combined ...
Shilang Liao   +10 more
semanticscholar   +1 more source

Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy.

Chemical Reviews, 2021
This review presents a robust strategy to design photosensitizers (PSs) for various species. Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the use of light combined with a light-activated chemical, referred to as a ...
Thanh Chung Pham   +4 more
semanticscholar   +1 more source

Conquering the Hypoxia Limitation for Photodynamic Therapy

Advances in Materials, 2021
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity.
Yilin Wan   +4 more
semanticscholar   +1 more source

Clinical Development of Metal Complexes as Photosensitizers for Photodynamic Therapy of Cancer.

Angewandte Chemie, 2021
Cancer has emerged over the last decades as one of the deadliest diseases in the world. Among the most commonly used techniques (i.e. surgery, immunotherapy, radiotherapy or chemotherapy), increasing attention has been devoted towards photodynamic ...
J. Karges
semanticscholar   +1 more source

Near Infrared Light Triggered Nitric Oxide-Enhanced Photodynamic Therapy and Low-Temperature Photothermal Therapy for Biofilm Elimination.

ACS Nano, 2020
Photothermal treatment (PTT) involving combination therapeutic modalities were recently emerged as an efficient alternative for combating biofilm. However, PTT-related local high temperature may destroy the surrounding healthy tissues. Herein, we present
Zhang Yuan   +7 more
semanticscholar   +1 more source

A Bacteria-Responsive Porphyrin for Adaptable Photodynamic/Photothermal Therapy.

Angewandte Chemie, 2022
We report a cationic porphyrin 5,10,15,20-tetrakis-(4-N-methylpyridyl)-porphyrin (TMPyP) that can respond to specific bacteria, followed by adaptable photodynamic/photothermal therapy processes.
Hao Hu   +4 more
semanticscholar   +1 more source

Organelle-Targeted Photosensitizers for Precision Photodynamic Therapy.

ACS Applied Materials and Interfaces, 2021
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell dysfunction and even death. Therefore, realizing precise organelle targeting of photosensitizers (PSs) can help reduce PS dosage, minimize side effects, avoid drug ...
Rui Wang, Xingshu Li, Juyoung Yoon
semanticscholar   +1 more source

Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies.

Chemical Society Reviews, 2021
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and immune activation ability.
Jianlei Xie   +14 more
semanticscholar   +1 more source

Nanomaterials in Antibacterial Photodynamic Therapy and Antibacterial Sonodynamic Therapy

Advanced Functional Materials
Antibacterial photodynamic therapy (aPDT) and antibacterial sonodynamic therapy (aSDT) utilize sensitizers (photosensitizers/sonosensitizers) to produce reactive oxygen species (ROS) for antibacterial treatment under the stimulation of light/ultrasound ...
Chaonan He   +7 more
semanticscholar   +1 more source

An Injectable Hydrogel for Simultaneous Photothermal Therapy and Photodynamic Therapy with Ultrahigh Efficiency Based on Carbon Dots and Modified Cellulose Nanocrystals

Advanced Functional Materials, 2021
The convenience of injectable hydrogels that can provide high loading of diverse phototherapy agents and further long‐time retention at the tumor site has attracted tremendous interest in simultaneous photothermal and photodynamic cancer therapies ...
Tianxing Chen   +6 more
semanticscholar   +1 more source

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