Results 121 to 130 of about 220,607 (288)

Hidden No More: Spotlight on Tidal Disruption Events in Active Galactic Nuclei

Astronomische Nachrichten, EarlyView.
ABSTRACT Tidal disruption events (TDEs) are typically discovered in previously quiescent galaxies. However, earlier studies have revealed a handful of TDEs occurring in pre‐existing active galactic nuclei (AGN). We discuss AT2019aalc, a promising TDE candidate in an AGN, and compare it to similar sources.
Patrik Milán Veres
wiley   +1 more source

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Influence of Zn2+ and Oxygen Supply on Malic Acid Production and Growth of Aspergillus oryzae

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Malic acid is a valuable platform chemical traditionally derived from fossil‐based resources. Microbial cultivation with Aspergillus oryzae offers a sustainable alternative based on renewable feedstocks. In this study, a well‐established minimal medium for malic acid production, commonly used in previous research to ensure reproducibility, was
Lukas Hartmann, Anke Neumann, Dirk Holtmann, Katrin Ochsenreither   +3 more
wiley   +1 more source

Photoinduced Electron Transfer (PET) as Key to Accelerate the Cycloreversion Reaction of Arylquadricyclanes

Chemistry – A European Journal, EarlyView.
It is demonstrated that the photoinduced cycloreversion of a methoxynaphthylquadricyclane in the presence of suitable photocatalysts gives quantitatively the corresponding norbornadiene. As this photochromic norbornadiene‐quadricyclane cycle has favorable properties for light energy conversion, this method provides a useful tool for the targeted ...
Julian Felix Maria Hebborn, Heiko Ihmels, Marco Löcker, Thomas Paululat, Robin Schulte   +4 more
wiley   +1 more source

Neue Versuche mit Spiropyran: Photometrie, NMR‐Spektroskopie und On‐Water‐Synthese

CHEMKON, EarlyView.
Reaktionskinetik wird häufig als schwierig, theoretisch und Mathematik‐lastig empfunden, weshalb experimentelle Zugänge für diesem Themenbereich notwendig sind. In diesem Beitrag werden entsprechende Versuche zur Reaktionskinetik vorgestellt, bei denen das Farbstoffsystem eines Spiropyrans und dessen isomerer Merocyanin‐Form untersucht wird.
Marcel Emmert, Jordan Karg, Katja Flora Weirauch   +2 more
wiley   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Photometric Diagnostic of the Sheath Dynamics and Electron Density Trends in Single and Dual Frequency CCRF Argon Plasmas

Contributions to Plasma Physics, EarlyView.
ABSTRACT A methodological study is presented on a noninvasive photometric diagnostic for determining trends in electron density and sheath dynamics in single (1f) and a dual (2f) radio frequency capacitively coupled (CCRF) argon plasmas. The 1f discharges are operated at 13.56 and 27.12 MHz, respectively, while the 2f discharge is driven by both ...
Daniel Zuhayra, Jessica Niemann, Viktor Schneider, Holger Kersten   +3 more
wiley   +1 more source

Tuning Colloidal Stability and Photothermal Conversion Efficiency of Graphite Nanofluids via Anionic‐Nonionic Surfactant Engineering

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Graphite nanofluids were stabilized using a mixed SDS/Tween 80 surfactant system. The optimized formulation exhibited enhanced colloidal stability, red‐shifted UV–Vis absorption, and improved photothermal conversion under solar irradiation. Achieving stable dispersion of graphite flakes (GFs) in aqueous media remains a critical challenge in developing ...
Ahmad Chehade, Shoaib Anwer, Md Islam, Eiyad Abu‐Nada   +3 more
wiley   +1 more source