Results 151 to 160 of about 51,612 (295)

A test of the Hapke photometric model [PDF]

open access: bronze, 2007
Michael K. Shepard, P. Helfenstein
openalex   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

Photometric scaling relations of lenticular and spiral galaxies [PDF]

open access: bronze, 2010
E. Laurikainen   +4 more
openalex   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz   +8 more
wiley   +1 more source

JWST interferometric imaging reveals the dusty torus obscuring the supermassive black hole of Circinus galaxy. [PDF]

open access: yesNat Commun
Lopez-Rodriguez E   +8 more
europepmc   +1 more source

Pristine dwarf galaxy survey – I. A detailed photometric and spectroscopic study of the very metal-poor Draco II satellite [PDF]

open access: bronze, 2018
Nicolas Longeard   +19 more
openalex   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof   +8 more
wiley   +1 more source

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